Bacterial Invasion into Eukaryotic Cells

Oelschlaeger, Tobias A.|Hacker, Jörg H.

ISBN 10: 0306462907 / ISBN 13: 9780306462900

Published by Springer US, 2000

About this Item

Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Introduction. Strategies of bacterial interaction with eukaryotic cells T.A. Oelschlaeger, J. Hacker. Nonprofessional Facultative Intracellular Bacteria. Microtubule dependent invasion pathways of bacteria T.A. Oelschlaeger, D.J. Kopecko. Interaction .

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Bibliographic Details

• Title: Bacterial Invasion into Eukaryotic Cells
• Publisher: Springer US
• Publication Date: 2000
• Language: English
• ISBN 10: 0306462907
• ISBN 13: 9780306462900
• Binding: Hardcover
• Condition: New

About this title

Synopsis

Strategies of Bacterial Interaction with Eukaryotic Cells *Tobias A. Oelschlaeger and Jorg Hacker 1. BENEFICIAL BACTERIAL-HOST INTERACTIONS Already during birth and soon thereafter mammals are colonized by bacte­ ria belonging to the resident microbial flora. Cutaneous and mucosal sur­ faces and the gastrointestinal tract are the areas which become colonized. These indigenous or autochthonous bacteria have a variety of beneficial effects on their hosts. They play a protective role by bacterial antagonism in fighting infections (Hoszowski and Truszczynski, 1997; Hentges, 1979). Pro­ duction of vitamin K is another essential contribution of the resident microbial flora to the health of the host (Hill, 1997). Even more important, studies with germ-free animals demonstrated the involvement of the microbial flora on the development of the immune system. Such animals have underdeveloped and relatively undifferentiated lymphoid tissues and low concentrations of serum immune globulins ( Cebra et at., 1998). They TOBIAS A. OELSCHLAEGER and JORG HACKER Institut filr Molekulare lnfektionsbiologie, Universitiit Wiirzburg, 97070 Wiirzburg, Germany. *Corresponding author; Phone: (0)931-312150; FAX: (0)931-312578; E-mail: t.oelschlaeger@mail.uni-wuerzburg.de xxix Tobias A. Oelschlaeger and Jorg Hacker also show defects in specific immune responsiveness and in nonspecific resistance induced by endotoxin, which may account for their lowered resis­ tance. A more typical example of symbiotic interaction of bacteria with a host are bacteria like Ruminococcus in the gut of ruminants, essential for degradation of cellulose (Hobson, 1988). The closest benefical bacterial-host interactions are those of intracellular symbiotic bacteria and their host cells.

Synopsis

This latest volume in the "Subcellular Biochemistry" series is an attempt to give an in-depth overview of the field of bacterial cell invasion. Late-20th century knowledge about all well-studied bacteria with the ability to invade eukaryotic cells is brought together, including bacteria pathogenic to humans and animals as well as the symbiotic rhizobia. Several chapters also deal with new approaches and applications regarding invasive bacteria. The book, which includes contributions from worldwide experts, discusses bacterial invasion ability within the context of bacteria-host cell interaction with the main focus on pathogenicity.