Antiinflammatory Styryl Derivatives: Design, Synthesis, and Biology

Language: English

Published by LAP LAMBERT Academic Publishing Mär 2014, 2014

3659218200 / 9783659218200

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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

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This item is printed on demand - it takes 3-4 days longer - Neuware -This book explains design, synthesis, and pharmacological properties of a series of substituted benzylidene acetone oxime ether derivatives from the corresponding oxime derivatives. The newly synthesized compounds were investigated in vivo for their antiinflammatory activities using carrageenin-induced rat paw oedema model. Among the compounds examined, compounds IVe and Vd showed the highest activity, nearly equivalent to that of the standard drug diclofenac sodium. Hence, they were screened for their analgesic activities using acetic acid-induced writhing model in mice and also, their ulcerogenic effects were studied. Compound Vd was found to possess significant antiinflammatory and analgesic activities with negligible ulcerogenic effect. In silico studies have been carried out. 140 pp. Englisch.

Seller Inventory # 9783659218200

Title
Antiinflammatory Styryl Derivatives: Design, Synthesis, and Biology
Author
Mohammed El-Gamal
Publisher
LAP LAMBERT Academic Publishing Mär 2014
Publication year
2014
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3659218200
ISBN 13
9783659218200
Item weight
227 grams
Dimensions
220x150x9 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

5-star seller

AbeBooks seller since January 11, 2012

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BuchWeltWeit Ludwig Meier e.K.

Germany