Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging is a comprehensive and timely book on all aspects of anti-aging strategies. The book provides comprehensive, foundational knowledge on the mechanisms of aging and current anti-aging strategies and approaches developed. Aging research has experienced an unprecedented advance over recent years with the discovery that the rate of aging is determined, at least to some extent, mainly by our genetics and modulated by environmental factors. The hallmarks of aging describe the molecular and cellular processes that govern biological aging and their variation in individuals.
- Covers different aspects of anti-aging research, from foundational knowledge to future perspectives
- Provides understanding on the different hallmarks of aging and how they can be applied in the development of anti-aging drugs
- Discusses various anti-aging strategies, including telomerase reactivation, clearance of senescent cells, stem cell-based therapy, and others
Dr. Sandeep Kumar Singh is Assistant Professor in the All India Institute of Medical Sciences (AIIMS), Nagpur, India. He obtained his PhD in Biotechnology from Banaras Hindu University and conducted postdoctoral research in the Department of Neurobiology at the University of Chicago. Dr. Singh brings 17 years of experience in neuroscience, molecular biology, neurodegenerative diseases, aging, nutraceuticals, and nanomedicines. He is a member of several scientific societies, including the American Academy of Neurology, International Society of Neurochemistry, Society of Neurochemistry, Indian Academy of Neurosciences, and Alzheimer’s and related Disorders Society of India. Dr. Singh has published five books, including Elsevier’s A New Era in Alzheimer’s Research and Genome Editing for Neurodegenerative Diseases.
Chih-Li Lin is a Professor and Research Fellow of Chung Shan Medical University and Hospital, Taiwan. He obtained his Ph. D. degree in the Institute of Biochemistry and Molecular Biology from National Taiwan University Medical College in 2007. Lin completed his postdoctoral research on the dementia & Alzheimer’s disease in National Taiwan University Hospital, and then moved to Institute of Medicine, Chung Shan Medical University (Taiwan) in 2008 and has been promoted to Full Professor in 2019. His major interests are to understand the pathophysiological connections between brain aging and Alzheimer’s dementia, particularly studying molecular mechanisms of amyloid beta (Aβ)-induced neurotoxicity, and applications of induced pluripotent stem (iPS) cell technology. He is currently working to demonstrate that brain insulin resistance may play roles in neuronal aging features and contribute to pathogenesis of Alzheimer's disease, Dementia with Lewy Bodies (DLB), and type 2 diabetes-associated dementia.
Shailendra Kumar Mishra is co-founder of Indian Scientific Education and Technology (ISET) Foundation, a non-profit/non-governmental organization that persuades toward the science promotion. He is Molecular Human Genetics postgraduate, skilled in DNA Sequencing, Polymerase Chain Reaction (PCR), DNA & Plasmid isolation, Gel electrophoresis, Molecular hybridization, DNA elution from agarose gel, bacterial transformation, quantitation of DNA, DNA sequencing technique and versed in various diagnostic techniques. He did Master of Science in Molecular and Human Genetics from Jiwaji University, India, and research project from Banaras Hindu University, India. He has published his articles in some international and national journals such as Journal of Alzheimer’s Disease and Parkinsonism and Nature India. His major interest is to understand the aging process through molecular basis that could be beneficial to cure age-related diseases.