Analyzing T Cell Responses : How to Analyze Cellular Immune Responses Against Tumor Associated Antigens

Language: English

Published by Springer, Netherlands, 2005

1402036221 / 9781402036224

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1402036221. Hardcover, from closed pharmaceutical company library. Lending record shows this book has never been borrowed. 313 pages, index, illustrated with charts, tables and diagrams. A critical assessment of all assays that have been used for the monitoring of antigen-specific immune responses. Emphasizes a global approach to the analysis of T cell mediated target/host interactions at the systemic and the peripheral level when such interactions are supposed to occur. Useful in the search of surrogate biomarkers predictive of treatment responsiveness and/or clinical outcome that are of interest to the biotechnology industry. Provides an overview of antigen-specific immune biology in human models of tumor and viral disease, discusses modulation of such responses through immune escape and presents cellular assays (cytoxicity, proliferation, cytokine production using ELISPOT, intracellular staining or cytometric assessment, detection of antigen-specific T cells with tetrameric HLA/epitope complexes or MHC-IG dimers, T cell receptor analysis, assessment of T cell receptor/HLA interactions using peptide/HLA-Green Fluorescent Protein complexes incorporation) and molecular assays including quantitative real-time PCR and gene profiling for evaluation of systemic and peripheral immune responses. Contents clean, tight and bright.

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Title
Analyzing T Cell Responses : How to Analyze Cellular Immune Responses Against Tumor Associated Antigens
Author
Dirk Nagorsen; F.M. Marincola
Publisher
Springer, Netherlands
Publication year
2005
Condition
Near Fine
Book Type
Book
Binding
Hardcover
Language
English
ISBN 10
1402036221
ISBN 13
9781402036224
Seller catalogs
Biotechnology

The Book Exchange

Macclesfield, Cheshire, United Kingdom

4-star seller

AbeBooks seller since December 12, 2003

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