Analytics of dissolution testing of products containing nanosized drugs with a view to predicting plasma profiles
Language: English
Published by Cuvillier
- Softcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
AbeBooks seller since August 14, 2006
Condition: New
£ 26.98
Quantity: 1 available
Add to basketItem description from seller
nach der Bestellung gedruckt Neuware - Printed after ordering - The oral bioavailability of a drug substance is strongly related to its aqueous solubility.Only complete dissolution during the GI-passage can maintain an optimalbioavailability. Poor aqueous drug solubility results, according to the Nernst-Brunnerequation into a slow dissolution rate, sometimes too slow for complete dissolution inthe GI tract. The dissolution rate increases with decreasing particle size and thereforeincreasing surface area of the drug particles. In consequence, micronization of thedrug is applied to increase oral bioavailability, but often meets with modest success.Recently developed techniques were applied to decrease the particle size into thenanometer range. For some substances, pharmacokinetic parameters could beinfluenced decisively, e.g. the obviation of a food effect for the drugs aprepitant andfenofibrate.
Seller Inventory # 9783954040001
Bibliographic details
- Title
- Analytics of dissolution testing of products containing nanosized drugs with a view to predicting plasma profiles
- Author
- Daniel Jünemann
- Publisher
- Cuvillier
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 395404000X
- ISBN 13
- 9783954040001
- Item weight
- 266 grams
- Dimensions
- 210x148x12 mm
Shipping rates from Germany to U.S.A.
| Item | 30 to 40 business days | 7 to 14 business days |
|---|---|---|
| First item | £ 51.91 | £ 60.38 |
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Kinderbücher & Kinderhör Casetten, German Books, Software, Natur & Tiere, Ratgeber, Sachbücher, Englische Bücher, Medizin & Gesundheit, Universität & StudiumSeller's business information
AHA-BUCH GmbH
Garlebsen 48
Einbeck, Germany 37574
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AHA-BUCH GmbH
represented by the managing director Christel Glass
Garlebsen 48
37574 Einbeck
Deutschland
Telefon: 055639996039
Telefax: 055639995974
E-Mail: abebooks@aha-buch.de
USt-IdNr.: DE261904229
registered at Commercial register Amtsgerichtes Göttingen
Handelsregisternummer HRB 200691
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