Analysis of Protein-Protein Interactions
Language: English
Published by AV Akademikerverlag Mai 2012, 2012
- Softcover
- New
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.
AbeBooks seller since January 11, 2012
Condition: New
£ 50.97
Quantity: 2 available
Add to basketItem description from seller
This item is printed on demand - it takes 3-4 days longer - Neuware -Revision with unchanged content. In the past years protein-protein interactions have gained a strong interest in the fields of pharmacy, medicine, biology, and bioinformatics. In this book, statistical information on protein-protein interactions are computationally collec ted and analyzed. Characteristic properties are determined and their predictability estimated. Therefore, the results from a common docking approach are re-evaluated with the collected information to discriminate structures with high yet biologically meaningless geometric complementarity at the interface region from the near native structures. The results show that although there is a noticeable improvement in the predictability after applying statistical information, the overall accuracy is still low. To find other more specific properties, transient and permanent complexes were compared to each other. The lack of data led to an extensive search for more suitable structural data and the development of an extensive database. This database was ultimately used to retrieve a large number of protein properties that were automatically analyzed for their separation precision. A high accuracy was obtained in separating transient and permanent interactions based on the combination of only four properties. Combining this information with common docking approaches based on geometrical complementarity may lead to satisfying sensitivities. 164 pp. Englisch.…
Seller Inventory # 9783639414677
- Title
- Analysis of Protein-Protein Interactions
- Author
- Sam Ansari
- Publisher
- AV Akademikerverlag Mai 2012
- Publication year
- 2012
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 3639414675
- ISBN 13
- 9783639414677
- Item weight
- 262 grams
- Dimensions
- 220x150x10 mm
"Synopsis" may belong to another edition of this title.
About the Author
"About the title" may belong to another edition of this title.
BuchWeltWeit Ludwig Meier e.K.
Bergisch Gladbach, Germany
AbeBooks seller since January 11, 2012
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