Advances in Second Messenger and Phosphoprotein Research, Volume 33 : Ion Channel Regulation
Language: English
Published by Academic Press, USA, 1998
- Hardcover
- Used
Seller: The Book Exchange, Macclesfield, Cheshire, United KingdomThe Book Exchange
AbeBooks seller since December 12, 2003
Condition: Used - Very good
£ 6.68
Quantity: 1 available
Add to basketItem description from seller
0120361337. Pictorial Board Hardcover, from closed pharmaceutical company library, light scuff on back cover. Appears unread, colour fade on spine. 334 pages, index, illustrated with charts, tables and diagrams. Volume 33: Reviews ion channel regulation by signal transduction pathways. Ion channels are no longer viewed simply as the voltage-gated resistors of biophysicists or the ligand-gated receptors of biochemists. They have been transformed during the past 20 years into signaling proteins that regulate every aspect of cell physiology. In addition to the voltage-gated channels, which provide the ionic currents to generate and spread neuronal activity, and the calcium ions to trigger synaptic transmission, hormonal secretion, and muscle contraction, new gene families of ion channel proteins regulate cell migration, cell cycle progression, apoptosis, and gene transcription, as well as electrical excitability. Even the genome of the lowly roundworm Caenorhabditis elegans encodes almost 100 distinct genes for potassium-selective channels alone. Most of these new channel proteins are insensitive to membrane potential, yet in humans, mutations in these genes disrupt development and increase individual susceptibility to debilitating and lethal diseases. How do cells regulate the activity of these channels? How might we restore their normal function? In "Ion Channel Regulation", many of the experts who pioneered these discoveries provide detailed summaries of our current understanding of the molecular mechanisms that control ion channel activity. Among its key features, it reviews brain function at the fundamental, molecular level; describes key systems that control signaling between and within cells; and explains how channels are used to stimulate growth and changes to activity of the nucleus and genome. Contents clean, tight and bright.…
Seller Inventory # 20581
- Title
- Advances in Second Messenger and Phosphoprotein Research, Volume 33 : Ion Channel Regulation
- Author
- David L. Armstrong; Sandra Rossie; Paul Greengard
- Publisher
- Academic Press, USA
- Publication year
- 1998
- Condition
- Very Good
- Book Type
- Book
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 0120361337
- ISBN 13
- 9780120361335
- Reviews brain functioning at the fundamental, molecular level
- Describes key systems that control signaling between and within cells
- Explains how channels are used to stimulate growth and changes to activity of the nucleus and genome
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The Book Exchange
Macclesfield, Cheshire, United Kingdom
AbeBooks seller since December 12, 2003
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