Synopsis
Precision medicine, inside the golden hour.
Most precision medicine is written for clinics that can wait days for a result. This atlas is written for the resuscitation bay, where the decision cannot wait at all.Every algorithm in these pages is actionable within sixty minutes, and every platform described here returns a usable result at the bedside or in a rapid on-site laboratory: point-of-care microfluidic PCR, isothermal amplification, and continuously available biomarkers. Assays whose turnaround is measured in days are deliberately excluded, because they cannot direct a decision that is being made now.
Built as an atlas, not as a reference wall.Every topic occupies a two-page spread and no more. The left page is a single visual decision flowchart running from triage, to a fast molecular test, to stratification, to action. The right page is high-yield content under three fixed headings: Molecular Target, Clinical Trap, and Actionable Protocol. Dose changes are never buried in prose. They appear in contrast tables that set standard blind therapy beside the genomic variant detected and the precision alternative, with the exact modification stated.
What is inside
- 112 decision flowcharts across fourteen chapters, from acute coronary syndrome to trauma
- A precision dosing contrast table in every chapter: standard therapy, variant detected, precision alternative
- BOARD TRAP boxes in every chapter, built on the conflict between legacy standard of care and modern precision protocol
- RED FLAG, BEDSIDE PEARL, EVIDENCE GRADE and WHY THIS DRUG panels throughout
- Every recommendation attributed to the body that issued it, with its evidence level named
- Appendices covering drug classes, decision thresholds with their issuing bodies, ultra-rapid platforms with reported turnaround, and how to read the evidence grades
CoverageFoundations of precision emergency medicine and the platforms that can meet the hour. Cardiovascular and neurovascular emergencies, including the CYP2C19 antiplatelet decision, thrombolysis tailoring, and anticoagulation reversal. Infection, sepsis and critical illness, including rapid pathogen and resistance detection and an honest account of where host-response phenotyping currently stands. Toxicology, severe cutaneous adverse reactions and analgesia, where metabolizer status has immediate consequences. Metabolic emergencies, trauma, special populations and department implementation.
Written forEmergency physicians and residents, critical care and trauma fellows, emergency pharmacists, acute care nurse practitioners and physician assistants, and students on emergency, intensive care and genetics rotations. Useful alongside preparation for emergency medicine and critical care examinations, where the distinction between a marker that predicts an outcome and one that directs a treatment is heavily tested.
This book is an educational reference for qualified healthcare professionals and supervised students. It is not a substitute for clinical judgement, local protocol, or current guidance and labelling, all of which should be checked before acting on any recommendation.
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"synopsis" may belong to another edition of this title.