Comprehensive Bioinformatic Investigation of Exonic SNPs of Candidate Genes for COVID-19 - Softcover
Synopsis
The work highlights the importance of functional characterization of single nucleotide polymorphisms (SNPs) associated with the risk for COVID-19. Using an in silico approach, exonic SNPs with potential functional impact and therapeutic value were identified, contributing to the development of personalized strategies to combat SARS-CoV-2 infection. This study, which uses in silico approaches to characterize exonic SNPs, highlights the importance of genomics in personalized medicine and the development of new therapeutic strategies. SNPs on IFIH1, NOS3, IL-6R, TYK2, EFNA4, PLSCR1, IFNA10, SLC22A31, P2RX7, TLR7, IFNL1 and DDX58 genes were the main SNPs analyzed here, based on a literature search in scientific databases, regarding pathogenicity, structural and functional impacts on proteins and signaling pathways related to the high risk of COVID-19 disease. The investigation of SNPs associated with COVID-19 provides valuable insights into how genetic variations may influence susceptibility and severity of infection. Functional analysis of synonymous and non-synonymous SNPs using advanced bioinformatics tools demonstrated that certain variants, such as sSNPs rs12252 in IFITM3 and rs731236 in VDR, have significant potential to impact mRNA structure and protein function, in addition to the nsSNP rs34536443 of TYK2 predicted to destabilize destabilize abilize the structure but also be capable of deleterious effects on the generated protein. The identification of deleterious SNPs suggests that some variants may predispose individuals to more severe forms of COVID-19, highlighting the need for genetic monitoring in vulnerable populations.
"synopsis" may belong to another edition of this title.
Search results for Comprehensive Bioinformatic Investigation of Exonic...
Stock Image
Comprehensive Bioinformatic Investigation of Exonic SNPs of Candidate Genes for COVID-19
Seller: PBShop.store UK, Fairford, GLOS, United Kingdom
Seller rating 5 out of 5 stars
PAP. Condition: New. New Book. Shipped from UK. Established seller since 2000. Seller Inventory # L2-9789999327732
Buy New
£ 43.23
£ 3.29 shipping
Ships from United Kingdom to U.S.A.
Ships from United Kingdom to U.S.A.
Quantity: Over 20 available
Stock Image
Comprehensive Bioinformatic Investigation of Exonic SNPs of Candidate Genes for COVID-19
Seller: Revaluation Books, Exeter, United Kingdom
Seller rating 5 out of 5 stars
Paperback. Condition: Brand New. 58 pages. 6.00x0.14x9.00 inches. In Stock. Seller Inventory # x-9999327737
Buy New
£ 40.97
£ 10 shipping
Ships from United Kingdom to U.S.A.
Ships from United Kingdom to U.S.A.
Quantity: 2 available
Stock Image
Comprehensive Bioinformatic Investigation of Exonic SNPs of Candidate Genes for COVID-19
Print on DemandSeller: Majestic Books, Hounslow, United Kingdom
Seller rating 4 out of 5 stars
Condition: New. Print on Demand. Seller Inventory # 407932106
Buy New
£ 45.24
£ 6.50 shipping
Ships from United Kingdom to U.S.A.
Ships from United Kingdom to U.S.A.
Quantity: 4 available
Stock Image
Comprehensive Bioinformatic Investigation of Exonic SNPs of Candidate Genes for COVID-19
Print on DemandSeller: Books Puddle, New York, NY, U.S.A.
Seller rating 4 out of 5 stars
Condition: New. Print on Demand. Seller Inventory # 26405222165
Stock Image
Comprehensive Bioinformatic Investigation of Exonic SNPs of Candidate Genes for COVID-19
Print on DemandSeller: Biblios, Frankfurt am main, HESSE, Germany
Seller rating 4 out of 5 stars
Condition: New. PRINT ON DEMAND. Seller Inventory # 18405222175
Stock Image
Comprehensive Bioinformatic Investigation of Exonic SNPs of Candidate Genes for COVID-19 (Paperback)
Print on DemandSeller: CitiRetail, Stevenage, United Kingdom
Seller rating 5 out of 5 stars
Paperback. Condition: new. Paperback. The work highlights the importance of functional characterization of single nucleotide polymorphisms (SNPs) associated with the risk for COVID-19. Using an in silico approach, exonic SNPs with potential functional impact and therapeutic value were identified, contributing to the development of personalized strategies to combat SARS-CoV-2 infection. This study, which uses in silico approaches to characterize exonic SNPs, highlights the importance of genomics in personalized medicine and the development of new therapeutic strategies. SNPs on IFIH1, NOS3, IL-6R, TYK2, EFNA4, PLSCR1, IFNA10, SLC22A31, P2RX7, TLR7, IFNL1 and DDX58 genes were the main SNPs analyzed here, based on a literature search in scientific databases, regarding pathogenicity, structural and functional impacts on proteins and signaling pathways related to the high risk of COVID-19 disease. The investigation of SNPs associated with COVID-19 provides valuable insights into how genetic variations may influence susceptibility and severity of infection. Functional analysis of synonymous and non-synonymous SNPs using advanced bioinformatics tools demonstrated that certain variants, such as sSNPs rs12252 in IFITM3 and rs731236 in VDR, have significant potential to impact mRNA structure and protein function, in addition to the nsSNP rs34536443 of TYK2 predicted to destabilize destabilize abilize the structure but also be capable of deleterious effects on the generated protein. The identification of deleterious SNPs suggests that some variants may predispose individuals to more severe forms of COVID-19, highlighting the need for genetic monitoring in vulnerable populations. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability. Seller Inventory # 9789999327732
Buy New
£ 40.99
£ 37 shipping
Ships from United Kingdom to U.S.A.
Ships from United Kingdom to U.S.A.
Quantity: 1 available
Seller Image
Comprehensive Bioinformatic Investigation of Exonic SNPs of Candidate Genes for COVID-19
Print on DemandSeller: AHA-BUCH GmbH, Einbeck, Germany
Seller rating 5 out of 5 stars
Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The work highlights the importance of functional characterization of single nucleotide polymorphisms (SNPs) associated with the risk for COVID-19. Using an in silico approach, exonic SNPs with potential functional impact and therapeutic value were identified, contributing to the development of personalized strategies to combat SARS-CoV-2 infection. This study, which uses in silico approaches to characterize exonic SNPs, highlights the importance of genomics in personalized medicine and the development of new therapeutic strategies.SNPs on IFIH1, NOS3, IL-6R, TYK2, EFNA4, PLSCR1, IFNA10, SLC22A31, P2RX7, TLR7, IFNL1 and DDX58 genes were the main SNPs analyzed here, based on a literature search in scientific databases, regarding pathogenicity, structural and functional impacts on proteins and signaling pathways related to the high risk of COVID-19 disease. The investigation of SNPs associated with COVID-19 provides valuable insights into how genetic variations may influence susceptibility and severity of infection.Functional analysis of synonymous and non-synonymous SNPs using advanced bioinformatics tools demonstrated that certain variants, such as sSNPs rs12252 in IFITM3 and rs731236 in VDR, have significant potential to impact mRNA structure and protein function, in addition to the nsSNP rs34536443 of TYK2 predicted to destabilize destabilize abilize the structure but also be capable of deleterious effects on the generated protein. The identification of deleterious SNPs suggests that some variants may predispose individuals to more severe forms of COVID-19, highlighting the need for genetic monitoring in vulnerable populations. Seller Inventory # 9789999327732
Seller Image
Comprehensive Bioinformatic Investigation of Exonic SNPs of Candidate Genes for COVID-19
Print on DemandSeller: preigu, Osnabrück, Germany
Seller rating 5 out of 5 stars
Taschenbuch. Condition: Neu. Comprehensive Bioinformatic Investigation of Exonic SNPs of Candidate Genes for COVID-19 | Marcos Jessé Abrahão Silva | Taschenbuch | Englisch | 2025 | Eliva Press | EAN 9789999327732 | Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, 36244 Bad Hersfeld, gpsr[at]libri[dot]de | Anbieter: preigu Print on Demand. Seller Inventory # 134228677