Developmental Origins of Health and Disease (DOHaD): From Biological Basis to Clinical Significance: 1012 (Advances in Experimental Medicine and Biology, 1012) - Softcover

Softcover

ISBN 10: 9811338566 ISBN 13: 9789811338564

Publisher: Springer, 2019

Synopsis

This book addresses the developmental origins of health and disease (DOHaD), a new medical concept that demonstrates that various adult diseases start in the fetal period. It discusses our current understanding of the molecular mechanisms of DOHaD, including gene body epigenetics and non-coding RNA, and comprehensively examines diseases such type 2 diabetes, a well known as standard DOHaD-associated disease, as well as non-alcoholic fatty liver disease, hypertension and neurodevelopmental disorders. It argues that most adult diseases start at a very early stage, such as in the fetal and neonatal periods, and that earlier prevention and intervention would result in better outcomes for adult diseases such as type 2 diabetes and cardiac disorders, which are increasing in both developed and developing countries. The book appeals to obstetricians and pediatricians, as well as physicians who treat adult patients, wanting to understand the origins of diseases.

About this title

About the Author

Takeo Kubota

Faculty of Child Studies, Seitoku University, Chiba, Japan

Hideoki Fukuoka

Research Institute for Science and Engineering, Waseda University, Tokyo, Japan

From the Back Cover

This book addresses the developmental origins of health and disease (DOHaD), a new medical concept that demonstrates that various adult diseases start in the fetal period. It discusses our current understanding of the molecular mechanisms of DOHaD, including gene body epigenetics and non-coding RNA, and comprehensively examines diseases such type 2 diabetes, a well known as standard DOHaD-associated disease, as well as non-alcoholic fatty liver disease, hypertension and neurodevelopmental disorders. It argues that most adult diseases start at a very early stage, such as in the fetal and neonatal periods, and that earlier prevention and intervention would result in better outcomes for adult diseases such as type 2 diabetes and cardiac disorders, which are increasing in both developed and developing countries. The book appeals to obstetricians and pediatricians, as well as physicians who treat adult patients, wanting to understand the origins of diseases.

Edition details

• Publisher: Springer
• Publication date: 2019
• Language: English
• ISBN 10: 9811338566
• ISBN 13: 9789811338564
• Binding: Paperback
• Number of pages: 102
• Editor: Kubota Takeo, Fukuoka Hideoki