Cell-free Circulating Dna: Purification And Analysis Techniques - Hardcover

 
9789811244674: Cell-free Circulating Dna: Purification And Analysis Techniques
Hardcover
ISBN 10: 9811244677 ISBN 13: 9789811244674
Publisher: World Scientific Publishing Co Pte Ltd, 2022

Synopsis

Circulating cell-free DNA is poised to transform cancer diagnosis and care; however, it carries technical challenges such as low abundance, fragmentation and sensitivity to biospecimen handling. Development of clinically useful assays hinges on understanding the unique technical aspects of working with cell-free DNA as a substrate. This book provides an in-depth summary of the technical issues impacting cell-free DNA purification from blood plasma and analysis in a cancer context, including design of PCR assays, sequencing library preparation and methylation analysis. Emerging fields such as extracellular vesicles and blood nucleases are also covered, as well as basic biology and considerations pertinent to biobanking.

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Publisher
World Scientific Publishing Co Pte Ltd
Publication date
2022
Language
English
ISBN 10 
9811244677
ISBN 13 
9789811244674
Binding
Hardcover
Number of pages
296
Editor
Warton Kristina, Samimi Goli