Moyamoya Disease Explored Through RNF213: Genetics, Molecular Pathology, and Clinical Sciences - Softcover

Softcover

ISBN 10: 9811027129 ISBN 13: 9789811027123

Publisher: Springer, 2017

Synopsis

Part I: Prologue.-
1. A prologue to moyamoya disease and RNF213.-
2. Concept of moyamoya Disease.-

Part II: Genetic Epidemiology.-
3. Molecular Epidemiology in East Asian Countries and in the World.-

Part III: Biochemistry, Function and Molecular Pathology.-

4. Molecular Biology of Mysterin/RNF213.-
5. Physiological Role of Mysterin/RNF213 in Zebrafish.-
6. Pathological Investigation on RNF213: Animal Models Knockout and Transgenic Mice in Diabetes and Signal Transduction.-
7. Pathological Investigation on RNF213: Animal Models of Rnf213-knockout and Knock-in Mice.-
8. RNF213 and Circulating Factors in Patients with Moyamoya Disease .-
9. Genetics of Moyamoya beyond RNF213.  Monogenic Moyamoya Syndromes.-

Part IV: Clinical Management

10. Natural History and Long-term Clinical Outcome after Conservative and Surgical Management.-
11. Significance of RNF213 in Clinical Management in Japan.-
12. Significance of RNF213 in Clinical Management in China.-
13. The Different Forms of Moyamoya Disease and Their Clinical Management.-
14. Vascular Diseases Attributable to RNF213 Other than Moyamoya Disease.-

Part V: Epilogue.-
Future Clinical Perspectives on RNF213 in Moyamoya Disease.

Edition details

• Publisher: Springer
• Publication date: 2017
• Language: English
• ISBN 10: 9811027129
• ISBN 13: 9789811027123
• Binding: Paperback