DNA Repair - On the Pathways to Fixing DNA Damage and Errors - Hardcover

Hardcover

ISBN 10: 9533076496 ISBN 13: 9789533076492

Publisher: IntechOpen, 2011

Synopsis

DNA repair is fundamental to all cell types to maintain genomic stability. A collection of cutting-edge reviews, DNA Repair - On the pathways to fixing DNA damage and errors covers major aspects of the DNA repair processes in a large variety of organisms, emphasizing foremost developments, questions to be solved and new directions in this rapidly evolving area of modern biology. Written by researchers at the vanguard of the DNA repair field, the chapters highlight the importance of the DNA repair mechanisms and their linkage to DNA replication, cell-cycle progression and DNA recombination. Major topics include: base excision repair, nucleotide excision repair, mismatch repair, double-strand break repair, with focus on specific inhibitors and key players of DNA repair such as nucleases, ubiquitin-proteasome enzymes, poly ADP-ribose polymerase and factors relevant for DNA repair in mitochondria and embryonic stem cells. This book is a journey into the cosmos of DNA repair and its frontiers.

Edition details

• Publisher: IntechOpen
• Publication date: 2011
• Language: English
• ISBN 10: 9533076496
• ISBN 13: 9789533076492
• Binding: Hardcover
• Number of pages: 394
• Editor: Storici Francesca