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Multifaceted Roles of Crystallography in Modern Drug Discovery (NATO Science for Peace and Security Series A: Chemistry and Biology) - Hardcover
The present work offers a snapshot of the state-of-the-art of crystallographic, analytical, and computational methods used in modern drug design and development. Topics discussed include: drug design against complex systems (membrane proteins, cell surface receptors, epigenetic targets, and ribosomes); modulation of protein-protein interactions; the impact of small molecule structures in drug discovery and the application of concepts such as molecular geometry, conformation, and flexibility to drug design; methodologies for understanding and characterizing protein states and protein-ligand interactions during the drug design process; and monoclonal antibody therapies. These methods are illustrated through their application to problems of medical and biological significance, such as viral and bacterial infections, diabetes, autoimmune disease, and CNS diseases. As approaches to drug discovery have changed over time, so have the methodologies used to solve the varied, new, and difficult problems encountered in drug discovery. In recent years we have seen great progress in the fields of genetics, biology, chemistry, and medicine, but there are still many unmet medical needs, from bacterial infections to cancer to chronic maladies, that require novel, different, or better therapies. This work will be of interest to researchers and policy makers interested in the latest developments in drug design.
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- PublisherSpringer
- Publication date2015
- ISBN 10 9401797188
- ISBN 13 9789401797184
- BindingHardcover
- Number of pages251
- EditorScapin Giovanna, Patel Disha, Arnold Eddy
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Multifaceted Roles of Crystallography in Modern Drug Discovery (NATO Science for Peace and Security Series A: Chemistry and Biology)
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Multifaceted Roles of Crystallography in Modern Drug Discovery
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Book Description Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The present work offers a snapshot of the state-of-the-art of crystallographic, analytical, and computational methods used in modern drug design and development. Topics discussed include: drug design against complex systems (membrane proteins, cell surface receptors, epigenetic targets, and ribosomes); modulation of protein-protein interactions; the impact of small molecule structures in drug discovery and the application of concepts such as molecular geometry, conformation, and flexibility to drug design; methodologies for understanding and characterizing protein states and protein-ligand interactions during the drug design process; and monoclonal antibody therapies. These methods are illustrated through their application to problems of medical and biological significance, such as viral and bacterial infections, diabetes, autoimmune disease, and CNS diseases. As approaches to drug discovery have changed over time, so have the methodologies used to solve the varied, new, and difficult problems encountered in drug discovery. In recent years we have seen great progress in the fields of genetics, biology, chemistry, and medicine, but there are still many unmet medical needs, from bacterial infections to cancer to chronic maladies, that require novel, different, or better therapies. This work will be of interest to researchers and policy makers interested in the latest developments in drug design. 252 pp. Englisch. Seller Inventory # 9789401797184
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Book Description Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Covering a variety of complementary experimental technologies Providing an up-to-date overview of structure based drug discovery and developmentDescribing macromolecule-centred and ligand-centred techniquesPresenting topics of intere. Seller Inventory # 16123404
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Book Description Hardcover. Condition: Brand New. 2015 edition. 254 pages. 9.25x6.25x0.75 inches. In Stock. Seller Inventory # x-9401797188
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Book Description Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - The present work offers a snapshot of the state-of-the-art of crystallographic, analytical, and computational methods used in modern drug design and development. Topics discussed include: drug design against complex systems (membrane proteins, cell surface receptors, epigenetic targets, and ribosomes); modulation of protein-protein interactions; the impact of small molecule structures in drug discovery and the application of concepts such as molecular geometry, conformation, and flexibility to drug design; methodologies for understanding and characterizing protein states and protein-ligand interactions during the drug design process; and monoclonal antibody therapies. These methods are illustrated through their application to problems of medical and biological significance, such as viral and bacterial infections, diabetes, autoimmune disease, and CNS diseases. As approaches to drug discovery have changed over time, so have the methodologies used to solve the varied, new, and difficult problems encountered in drug discovery. In recent years we have seen great progress in the fields of genetics, biology, chemistry, and medicine, but there are still many unmet medical needs, from bacterial infections to cancer to chronic maladies, that require novel, different, or better therapies. This work will be of interest to researchers and policy makers interested in the latest developments in drug design. Seller Inventory # 9789401797184
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Book Description Condition: New. Editor(s): Patel, Disha; Arnold, Eddy; Scapin, Giovanna. Series: NATO Science for Peace and Security Series A: Chemistry and Biology. Num Pages: 251 pages, 18 black & white illustrations, 89 colour illustrations, biography. BIC Classification: MBGR; PHFC; PNRP; PSB. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 16. Weight in Grams: 543. . 2015. Hardback. . . . . Seller Inventory # V9789401797184
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