Synopsis
List of contributors. Preface. Modelling of anaesthetic action: The effect site. Physiological modelling and the effect site; M. Weiss. Targeting the effect site; J.G. Bovill. Effect sites of intravenous anaesthetic agents; K. Morita, et al. Exploring the plasma-effect site concentration difference during effect site controlled infusion; C. Moiny, et al. Genetic models and mapping genes in the study of anaesthetic action; V.J. Simpson, et al. The perioperative use of hypnotic agents. Total intravenous anaesthesia: the equipment; F.H.M. Engbers. Closed loop control of general anaesthesia; A. Absolom, G.N.C. Kenny. The effect of opioids on the pharmacokinetics and pharmacodynamics of propofol; J. Vuyk. Strategies to prevent awareness; M. Struys, et al. Patient controlled sedation during locoregional anaesthesia; N. Sutcliffe, D. Amutike. Target controlled sedation in the intensive care unit; S.M. Groen-Mulder. State of the art on neuromuscular blockade. Computer-controlled infusion of neuromuscular blocking agents; V. Billard, P. Mavoungou. New neuromuscular blocking agents and fast-tracking anaesthesia; H. Mellinghoff. Neuromuscular blocking agents in the elderly; F. Servin. The use of neuromuscular blocking agents in the ICU; K.S. Khünl-Brady. Neuromuscular blocking agents and neuromuscular diseases; B. Plaud, F. Donati. Sites of respiratory action of opioids; E. Sarton, A. Dahan. Remifentanil - a new age in anaesthesia? J. Raeder. Monitored anaesthesia care with remifentanil; J.R. Sneyd, A. Craig. Remifentanil anaesthesia and postoperative pain management; S. Schraag. Target controlled infusion for postoperative analgesia; M.C.O.van den Nieuwenhuyzen. Serotonin: its implications in postoperative nausea and vomiting; A. Borgeat.
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