Items related to Metal Compounds in Cancer Therapy

Metal Compounds in Cancer Therapy - Softcover

 
9789401045452: Metal Compounds in Cancer Therapy

Synopsis

The discovery of the antitumour activity of cisplatin in 1965 and its subsequent introduction into clinical trials in 1971 was the catalyst for a major international research effort investigating the potential of metal compounds in cancer therapy. Cisplatin now occupies an important place in the armamentarium of the oncologist due to its effectiveness in the treatment of testicular cancer. A second generation analogue, carbo­ platin, offers reduced toxicity together with therapeutic activity, which gives it a place in the front-line therapy of genitourinary cancers. These and other successes have encouraged the search for novel metal-based drugs for cancer therapy. Research has shown that metal compounds have potential for activity not only as cytotoxic antitumour agents, but also in areas such as adjuvant therapy, diagnosis and immunotherapy. The aim of this book is to review and describe the major achievements and developments arising from this international research effort. The contributing authors come from labora­ tories throughout Europe and America and represent the many disci­ plines characteristic of this research, such as clinical research, pharmacology, tumour biology and inorganic medicinal chemistry.

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Product Description

The discovery of the anti-tumour activity of cisplatin in 1965 and its subsequent introduction into clinical trials in 1971 was the catalyst for a major research effort into the potential of metal compounds in cancer therapy. This book draws together information on all metals involved in cancer therapy, including those used in radioisotopes. Throughout an interdisciplinary approach has been taken to reflect the nature of this research. This book will provide an invaluable reference source for anyone interested in the role of metals in oncotherapy.

Review

...provides a helpful entry and useful references to an advancing area mainly from the biochemical standpoint - Human & Experimental Toxicology; For those in the area it is an essential reading/reference work... It is an important series to launch at this time and is strongly recommended. - Platinum Metals Review

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