DNA Methods in Clinical Microbiology - Softcover

Singleton, P.

Softcover

ISBN 10: 9048154561 ISBN 13: 9789048154562

Publisher: Springer, 2010

Synopsis

DNA Methods in Clinical Microbiology describes the novel DNA-based technology now used in the diagnosis and management of infectious diseases. It is a concise, yet readable, overview written primarily for clinicians, clinical microbiologists, medical students and undergraduates in medical and veterinary microbiology.
The book has two primary aims. First, to explain the principles of these methods at the `molecular' level. Second, to provide a clinical perspective by reporting results from actual DNA-based investigations on a range of specimens.
Those approaching DNA methods for the first time are assisted by a brief résumé of the relevant features of nucleic acids (Chapter 2): this information is essential for an understanding of later chapters. Subsequent text covers detection, characterization and quantification of pathogens by a variety of methods - e.g., target amplification (PCR, LCR, NASBA, TMA and SDA), signal amplification (bDNA) and probe-based techniques; the chapter on typing describes nearly twenty named molecular methods, including spoligotyping and MLST. All chapters include an adequate range of current reference from which, if required, detailed protocols can be obtained. The diagrams are clear, and readers are assisted by a detailed index.

About this title

Review

"This is a very rich and exceedingly well-written book. I learned a lot."
(Dan Ryder, University of Connecticut, U.S.A., Synthese 141:2)

From the Back Cover

This book contains substantially extended and revised versions of the best papers from the 12th International Conference on Enterprise Information Systems (ICEIS 2010), held in Funchal, Madeira, Portugal, June 8-12, 2010.

Two invited papers are presented together with 39 contributions, which were carefully reviewed and selected from 62 full papers presented at the conference (out of 448 submissions). They reflect state-of-the-art research work that is often driven by real-world applications, thus successfully relating the academic with the industrial community. The topics covered are: databases and information systems integration, artificial intelligence and decision support systems, information systems analysis and specification, software agents and internet computing, and human-computer interaction.

Edition details

• Publisher: Springer
• Publication date: 2010
• Language: English
• ISBN 10: 9048154561
• ISBN 13: 9789048154562
• Binding: Paperback
• Number of pages: 264