Hemoglobin Function in Vertebrates: Molecular Adaptation in Extreme and Temperate Environments - Hardcover

Hardcover

ISBN 10: 8847001072 ISBN 13: 9788847001077

Publisher: Springer, 2000

Synopsis

The annual Congress of the Italian Biochemical and Molecular Biology Society (SIB) was held in September 1999 in Alghero, Sardegna, Italy. The programme envisaged a symposium on molecular adaptations of haemoglobin function in ver­ tebrates. Haemoglobin specialists from several countries were invited to speak at the symposium and paved the way for wide-ranging and stimulating discussions. The symposium contributions have been collected together in this volume. The structure/function relationship in haemoglobins from vertebrates (fishes populat­ ing temperate and polar environments, diving birds, marine and terrestrial mam­ mals) has been tackled from many angles, focusing on the adaptation of the oxy­ gen-transport system to the constraints dictated by the environment. Eleven arti­ cles review some of the most recent developments of the studies on this ancient oxygen-transport protein, characterized by high conservation during evolution. The volume offers the reader an updated, state-of-the-art summary of a field that is enjoying a true renaissance. Covering the topic from several viewpoints, the volume includes protein chemistry (amino acid sequence, secondary, tertiary and quaternary structures, thermodynamics of oxygen-binding features), molecular biology (globin gene structure, sequence, organization, expression and regulation) and evolution. In this representation of effective multidisciplinary and multina­ tional collaborative efforts, reference is available to a wide range of disciplines and biological systems. The tools of the investigators comprise advanced and powerful methodologies developed in recent years, e. g.

About this title

Product Description

Rare Book

Synopsis

This volume comprises selected contributions by internationally renowned researchers and represents the state-of-the-art in the field of hemoglobin function in vertebrates living in extreme and temperate environments. The topics have been covered from several viewpoints, including protein chemistry, molecular biology, and evolution. All the contributions chosen for publication focus on phenotypic and genetic adaptations to changing environmental conditions and on gene expression and regulation. The book provides the reader with an update in this field, which is presently enjoying a true renaissance following developments in recent years of powerful methodologies such as site-directed mutagenesis and discoveries of new roles, for example, as oxygen sensors and in nitric oxide metabolism.

Edition details

• Publisher: Springer
• Publication date: 2000
• Language: English
• ISBN 10: 8847001072
• ISBN 13: 9788847001077
• Binding: Hardcover
• Number of pages: 132
• Editor: Prisco G. Di, Giardina B., Weber R.E.