Development of Lanthanide Metal Complexes for Biomedical Applications: Schiff Based Ligand Approach for Metal Complexes - Softcover

B O, MR Gajendra; Sowbhagya, Dr; M, Dr Mylarappa

 
9786209256127: Development of Lanthanide Metal Complexes for Biomedical Applications: Schiff Based Ligand Approach for Metal Complexes
Softcover
ISBN 10: 6209256120 ISBN 13: 9786209256127
Publisher: LAP Lambert Academic Publishing, 2025

Synopsis

This book presents the synthesis, characterization and biomedical applications of lanthanide Schiff base complexes from specially designed organic ligands. Examples of these complexes are readily available through a controlled coordination reaction between Ln(III) ions and multidentate Schiff base ligands developed to stabilize and define the metal-ion coordination bond. A variety of advanced analytical characterization methods including FT-IR, UV-Vis, NMR, Mass spectrometry, SEM-EDX, TGA, and XRD were used to study the multivalent ligands and assess structural properties, coordination abilities, elemental make-up, morphology and thermal properties of the synthesized complexes. Using standard microbiology and cytotoxicity assay routes, the antimicrobial and anticancer properties of the complexes have been rigorously studied to demonstrate significant inhibition against selected strains of bacteria, fungi and cancer cell-lines. The results further suggest that Schiff base lanthanide complexes exhibit significant therapeutic impact and could provide effective bioactive agents for future biomedical studies and drug-design research.

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Publisher
LAP Lambert Academic Publishing
Publication date
2025
Language
English
ISBN 10 
6209256120
ISBN 13 
9786209256127
Binding
Paperback
Number of pages
52