Container-content interactions: Theoretical and practical aspects - Softcover

Souissi, Nour Elhouda; Ben Cheikh, Mohamed Hedi

 
9786208537104: Container-content interactions: Theoretical and practical aspects
Softcover
ISBN 10: 620853710X ISBN 13: 9786208537104
Publisher: Our Knowledge Publishing, 2025

Synopsis

In the pharmaceutical sector, container-content interactions refer to the transfer of substances between manufacturing equipment, packaging or medical devices, and the drug. These phenomena include the adsorption of active ingredients or excipients onto container walls, their penetration into the interior of materials or their diffusion into the external environment. In addition, these phenomena include the migration of substances from the container to the drug, or from the external environment to the drug.Such interactions can compromise the quality, efficacy and safety of pharmaceutical products, leading to potentially serious adverse effects for patients, such as changes in therapeutic efficacy or toxic reactions.In this work, we have reported on examples of container-content interactions, specifying the circumstances in which they occur, the methodologies used to study them and their impact on both the drug and the patient.

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Publisher
Our Knowledge Publishing
Publication date
2025
Language
English
ISBN 10 
620853710X
ISBN 13 
9786208537104
Binding
Paperback
Number of pages
92