MISOPROSTOL IN CERVICAL RIPENING - Softcover

Bergaoui, HAYFA; GHADHAB, IMEN; BELHAJ, YESSINE

Softcover

ISBN 10: 6208229642 ISBN 13: 9786208229641

Publisher: Our Knowledge Publishing, 2024

Synopsis

Premature rupture of the membranes is a frequent obstetrical condition. It affects 8 to 10% of full-term pregnancies, and its optimal management is controversial. Among the agents used to promote cervical ripening are prostaglandins, of which Dinoprostone is the reference molecule.Material and methods This is a prospective, randomized clinical trial conducted at the maternity and neonatology center of Monastir University Hospital over a period of 1 year (January-December 2017).Including 240 parturients presenting with RPM at term and divided into 2 groups:The "oral route" group: having received 20mcg/ 2h misoprostol solution orally (maximum 6 doses) and the "vaginal route" group:having received 50mcg/ 6h misoprostol vaginally (maximum 4 doses).Conclusion At the end of this study, the use of low-dose misoprostol by VO for cervical ripening at term, with PDER, is as effective as VV in terms of the rate of deliveries within 24 h, while it is slightly ahead at 12 h (44% versus 33%) without the difference being significant.

Edition details

• Publisher: Our Knowledge Publishing
• Publication date: 2024
• Language: English
• ISBN 10: 6208229642
• ISBN 13: 9786208229641
• Binding: Paperback
• Number of pages: 52