Smoking control is one of the biggest challenges for public health promotion, as it is responsible for high mortality rates which could be avoided. Studies show that the components derived from cigarette combustion cause epigenetic changes, such as methylation of the DNA molecule. This alteration causes gene silencing, resulting in a lack of gene expression and contributing to the phenotypic expression of various diseases, especially cancers, cardiovascular and lung diseases. Telomeres, on the other hand, are DNA-protein complexes that promote genome stability. They are located at the ends of eukaryotic chromosomes and in humans are represented by repetitive sequences of 6 nucleotides (TTAGGG)n. Telomere shortening occurs with each cell replication and this reduction leads to cellular senescence and apoptosis. Oxidative stress is one of the factors that accelerates telomere shortening and tobacco smoking contributes to this stress. Studies show a clear correlation between tobacco consumption, oxidative stress, early telomere shortening and inadequate DNA methylation.
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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 52 pp. Englisch. Seller Inventory # 9786207329670
Seller: AHA-BUCH GmbH, Einbeck, Germany
Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Smoking control is one of the biggest challenges for public health promotion, as it is responsible for high mortality rates which could be avoided. Studies show that the components derived from cigarette combustion cause epigenetic changes, such as methylation of the DNA molecule. This alteration causes gene silencing, resulting in a lack of gene expression and contributing to the phenotypic expression of various diseases, especially cancers, cardiovascular and lung diseases. Telomeres, on the other hand, are DNA-protein complexes that promote genome stability. They are located at the ends of eukaryotic chromosomes and in humans are represented by repetitive sequences of 6 nucleotides (TTAGGG)n. Telomere shortening occurs with each cell replication and this reduction leads to cellular senescence and apoptosis. Oxidative stress is one of the factors that accelerates telomere shortening and tobacco smoking contributes to this stress. Studies show a clear correlation between tobacco consumption, oxidative stress, early telomere shortening and inadequate DNA methylation. Seller Inventory # 9786207329670
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germany
Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Smoking control is one of the biggest challenges for public health promotion, as it is responsible for high mortality rates which could be avoided. Studies show that the components derived from cigarette combustion cause epigenetic changes, such as methylation of the DNA molecule. This alteration causes gene silencing, resulting in a lack of gene expression and contributing to the phenotypic expression of various diseases, especially cancers, cardiovascular and lung diseases. Telomeres, on the other hand, are DNA-protein complexes that promote genome stability. They are located at the ends of eukaryotic chromosomes and in humans are represented by repetitive sequences of 6 nucleotides (TTAGGG)n. Telomere shortening occurs with each cell replication and this reduction leads to cellular senescence and apoptosis. Oxidative stress is one of the factors that accelerates telomere shortening and tobacco smoking contributes to this stress. Studies show a clear correlation between tobacco consumption, oxidative stress, early telomere shortening and inadequate DNA methylation.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 52 pp. Englisch. Seller Inventory # 9786207329670