Items related to Effectiveness and Safety of Radium-223 Dichloride:...

Effectiveness and Safety of Radium-223 Dichloride: Modifications in its indication - Softcover

Asensio Ruiz, Mª Alejandra; Soria Soto, Manuel

 
9786206581642: Effectiveness and Safety of Radium-223 Dichloride: Modifications in its indication

Synopsis

Radium-223 dichloride (Ra-223) is an alpha particle-emitting radiopharmaceutical whose licensed indication in patients with castration-resistant prostate cancer with bone metastases (CRPCm) was modified in June 2018, due to the appearance of drug-drug interactions with common drugs in CRPCm such as abiraterone and prednisone/prednisolone. Thus, it was restricted to use in monotherapy or combination with luteinizing hormone-releasing hormone analogues, becoming third-line treatment in patients with CRPCm, for which evidence on its effectiveness and safety in this new context is lacking.

"synopsis" may belong to another edition of this title.