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Structure Activity Relationship of Drugs of Abuse: Synthetic Cannabinoids, Synthetic Cathinones and Fentanyl analogues - Softcover
Synopsis
Structures of novel psychoactive substances are based on the structure activity relationship (SAR) of existing drugs of abuse. The study identified links between structural modifications and toxicities, adverse and physiological effects of cannabinoids, cathinones and opioids. Literature review identified the structural backbone, toxicities, adverse and physiological effects of cannabinoids, cathinones and opioids. SAR of cannabinoids, cathinones and opioids was based on amino alkylindoles, cathinone derivatives and fentanyl derivatives. Synthetic cannabinoids XLR-11 and MDMB-CHMICA have been linked to acute kidney injury due to over stimulation of CB1 receptors. The synthetic cathinones MDPV and α-PVP cause a higher occurrence of psychosis and delirium compared to other synthetic cathinones due to inhibitory uptake effects at dopamine and norepinephrine transporters. Fentanyl analogues having a lower lipophilic value than fentanyl had a shorter duration of physiological effects compared to fentanyl analogues having higher lipophilic values than fentanyl. The study contributes to an explanation of the higher potencies, toxicities and adverse effects associated with synthetic drugs.
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Structure Activity Relationship of Drugs of Abuse
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LAP LAMBERT Academic Publishing Dez 2018, 2018
ISBN 10: 613993267X
ISBN 13: 9786139932672
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Taschenbuch
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Structures of novel psychoactive substances are based on the structure activity relationship (SAR) of existing drugs of abuse. The study identified links between structural modifications and toxicities, adverse and physiological effects of cannabinoids, cathinones and opioids. Literature review identified the structural backbone, toxicities, adverse and physiological effects of cannabinoids, cathinones and opioids. SAR of cannabinoids, cathinones and opioids was based on amino alkylindoles, cathinone derivatives and fentanyl derivatives. Synthetic cannabinoids XLR-11 and MDMB-CHMICA have been linked to acute kidney injury due to over stimulation of CB1 receptors. The synthetic cathinones MDPV and -PVP cause a higher occurrence of psychosis and delirium compared to other synthetic cathinones due to inhibitory uptake effects at dopamine and norepinephrine transporters. Fentanyl analogues having a lower lipophilic value than fentanyl had a shorter duration of physiological effects compared to fentanyl analogues having higher lipophilic values than fentanyl. The study contributes to an explanation of the higher potencies, toxicities and adverse effects associated with synthetic drugs. 268 pp. Englisch. Seller Inventory # 9786139932672
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Structure Activity Relationship of Drugs of Abuse
Published by
LAP LAMBERT Academic Publishing, 2018
ISBN 10: 613993267X
ISBN 13: 9786139932672
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Softcover
Seller: moluna, Greven, Germany
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Axisa KerstyKersty Axisa is a pharmaceutical technology graduate who is currently undertaking an International Fellowship programme with the Advanced Scientific Initiative directorate at the Malta Medicines Authority. Kersty is plann. Seller Inventory # 385877961
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Structure Activity Relationship of Drugs of Abuse | Synthetic Cannabinoids, Synthetic Cathinones and Fentanyl analogues
Published by
LAP LAMBERT Academic Publishing, 2018
ISBN 10: 613993267X
ISBN 13: 9786139932672
New
Taschenbuch
Seller: preigu, Osnabrück, Germany
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Taschenbuch. Condition: Neu. Structure Activity Relationship of Drugs of Abuse | Synthetic Cannabinoids, Synthetic Cathinones and Fentanyl analogues | Kersty Axisa (u. a.) | Taschenbuch | 268 S. | Englisch | 2018 | LAP LAMBERT Academic Publishing | EAN 9786139932672 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Seller Inventory # 115140734
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Structure Activity Relationship of Drugs of Abuse
Published by
LAP LAMBERT Academic Publishing Dez 2018, 2018
ISBN 10: 613993267X
ISBN 13: 9786139932672
New
Taschenbuch
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germany
Seller rating 5 out of 5 stars
Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Structures of novel psychoactive substances are based on the structure activity relationship (SAR) of existing drugs of abuse. The study identified links between structural modifications and toxicities, adverse and physiological effects of cannabinoids, cathinones and opioids. Literature review identified the structural backbone, toxicities, adverse and physiological effects of cannabinoids, cathinones and opioids. SAR of cannabinoids, cathinones and opioids was based on amino alkylindoles, cathinone derivatives and fentanyl derivatives. Synthetic cannabinoids XLR-11 and MDMB-CHMICA have been linked to acute kidney injury due to over stimulation of CB1 receptors. The synthetic cathinones MDPV and ¿-PVP cause a higher occurrence of psychosis and delirium compared to other synthetic cathinones due to inhibitory uptake effects at dopamine and norepinephrine transporters. Fentanyl analogues having a lower lipophilic value than fentanyl had a shorter duration of physiological effects compared to fentanyl analogues having higher lipophilic values than fentanyl. The study contributes to an explanation of the higher potencies, toxicities and adverse effects associated with synthetic drugs.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 268 pp. Englisch. Seller Inventory # 9786139932672
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Structure Activity Relationship of Drugs of Abuse : Synthetic Cannabinoids, Synthetic Cathinones and Fentanyl analogues
Published by
LAP LAMBERT Academic Publishing, 2018
ISBN 10: 613993267X
ISBN 13: 9786139932672
New
Taschenbuch
Seller: AHA-BUCH GmbH, Einbeck, Germany
Seller rating 5 out of 5 stars
Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Structures of novel psychoactive substances are based on the structure activity relationship (SAR) of existing drugs of abuse. The study identified links between structural modifications and toxicities, adverse and physiological effects of cannabinoids, cathinones and opioids. Literature review identified the structural backbone, toxicities, adverse and physiological effects of cannabinoids, cathinones and opioids. SAR of cannabinoids, cathinones and opioids was based on amino alkylindoles, cathinone derivatives and fentanyl derivatives. Synthetic cannabinoids XLR-11 and MDMB-CHMICA have been linked to acute kidney injury due to over stimulation of CB1 receptors. The synthetic cathinones MDPV and -PVP cause a higher occurrence of psychosis and delirium compared to other synthetic cathinones due to inhibitory uptake effects at dopamine and norepinephrine transporters. Fentanyl analogues having a lower lipophilic value than fentanyl had a shorter duration of physiological effects compared to fentanyl analogues having higher lipophilic values than fentanyl. The study contributes to an explanation of the higher potencies, toxicities and adverse effects associated with synthetic drugs. Seller Inventory # 9786139932672
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Structure Activity Relationship of Drugs of Abuse
Published by
LAP Lambert Academic Publishing, 2018
ISBN 10: 613993267X
ISBN 13: 9786139932672
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Seller: Mispah books, Redhill, SURRE, United Kingdom
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paperback. Condition: New. NEW. SHIPS FROM MULTIPLE LOCATIONS. book. Seller Inventory # ERICA823613993267X6