Modeling of Bio-Activity and Toxicity in Light of NA Bases Interaction: QSAR Modeling through NA Bases Interaction - Softcover
Synopsis
Biological activity and toxicity of molecules are the major aspects on understanding diverse bio-mechanisms in living systems. Estimation of degree of activity and toxicity of molecules in a target is very important for their control and applications. However, experimental determination of bio-activity or toxicity is a mammoth task due to cost, time and availability of resources. In this direction, a fruitful mathematical approach has been successfully developed as Quantitative Structure Activity Relationship (QSAR). A successful QSAR modeling can also predict the bio-activity and toxicity of unknown homologous compounds. The present book addresses details of QSAR methods and relevant statistical analysis, various structural descriptors along with a couple of case studies considering important role of nucleic acid bases during the interaction of bio-active/toxic molecules with biological targets. The bio-activity of a series of acyl-CoA: cholesterol O-acyltransferase (ACAT) inhibitors, viz. aminosulfonyl ureas and toxicity of a series of Polycyclic Aromatic Hydrocarbons (PAHs) are reported in light of their interaction with model bio-systems.
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Mondal Roy SutapaDr. Mondal Roy is an Asst. Prof. of Chemistry at Uka-Tarsadia Univ, Bardoli, India and obtained Ph.D. from Jadavpur Univ, Kolkata. Over 20 of her publications are cited with h-index 8. Dr. Roy is an Asso. Prof. of Ph. Seller Inventory # 385853540
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Modeling of Bio-Activity and Toxicity in Light of NA Bases Interaction : QSAR Modeling through NA Bases Interaction
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Biological activity and toxicity of molecules are the major aspects on understanding diverse bio-mechanisms in living systems. Estimation of degree of activity and toxicity of molecules in a target is very important for their control and applications. However, experimental determination of bio-activity or toxicity is a mammoth task due to cost, time and availability of resources. In this direction, a fruitful mathematical approach has been successfully developed as Quantitative Structure Activity Relationship (QSAR). A successful QSAR modeling can also predict the bio-activity and toxicity of unknown homologous compounds. The present book addresses details of QSAR methods and relevant statistical analysis, various structural descriptors along with a couple of case studies considering important role of nucleic acid bases during the interaction of bio-active/toxic molecules with biological targets. The bio-activity of a series of acyl-CoA: cholesterol O-acyltransferase (ACAT) inhibitors, viz. aminosulfonyl ureas and toxicity of a series of Polycyclic Aromatic Hydrocarbons (PAHs) are reported in light of their interaction with model bio-systems. Seller Inventory # 9786138910275
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Modeling of Bio-Activity and Toxicity in Light of NA Bases Interaction | QSAR Modeling through NA Bases Interaction
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Taschenbuch. Condition: Neu. Modeling of Bio-Activity and Toxicity in Light of NA Bases Interaction | QSAR Modeling through NA Bases Interaction | Sutapa Mondal Roy (u. a.) | Taschenbuch | Englisch | Scholar's Press | EAN 9786138910275 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Seller Inventory # 117440310