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Design & Evaluation of Controlled Release Matrix Tablets of Prazosin: Modern Management of Hypertension - Softcover

 
9786138387824: Design & Evaluation of Controlled Release Matrix Tablets of Prazosin: Modern Management of Hypertension

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In the present study, we have prepared matrix tablet formulations using Prazocin as a model drug and Ethyl Cellulose, Two grades of Hydroxy Propyl Methyl Cellulose- HPMC-K4M & HPMC-K100M as polymers in different ratios. The developed matrix tablets were evaluated for different physical-chemical evaluations like drug content, hardness, friability, swelling index etc. All the formulations had shown the results within prescribed limits. The In vitro drug release study indicates that formulation PCF-7 containing EC, HPMC K100M in 1:2 ratio shown good release pattern for 14 hours compares to other formulations. The short-term stability study proved no change in the formulation of ageing and it indicates good stability.

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  • PublisherLAP LAMBERT Academic Publishing
  • Publication date2018
  • ISBN 10 6138387821
  • ISBN 13 9786138387824
  • BindingPaperback
  • LanguageEnglish
  • Number of pages76

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Rajan Kothari
ISBN 10: 6138387821 ISBN 13: 9786138387824
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In the present study, we have prepared matrix tablet formulations using Prazocin as a model drug and Ethyl Cellulose, Two grades of Hydroxy Propyl Methyl Cellulose- HPMC-K4M & HPMC-K100M as polymers in different ratios. The developed matrix tablets were evaluated for different physical-chemical evaluations like drug content, hardness, friability, swelling index etc. All the formulations had shown the results within prescribed limits. The In vitro drug release study indicates that formulation PCF-7 containing EC, HPMC K100M in 1:2 ratio shown good release pattern for 14 hours compares to other formulations. The short-term stability study proved no change in the formulation of ageing and it indicates good stability. 76 pp. Englisch. Seller Inventory # 9786138387824

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Rajan Kothari
Published by LAP LAMBERT Academic Publishing, 2018
ISBN 10: 6138387821 ISBN 13: 9786138387824
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - In the present study, we have prepared matrix tablet formulations using Prazocin as a model drug and Ethyl Cellulose, Two grades of Hydroxy Propyl Methyl Cellulose- HPMC-K4M & HPMC-K100M as polymers in different ratios. The developed matrix tablets were evaluated for different physical-chemical evaluations like drug content, hardness, friability, swelling index etc. All the formulations had shown the results within prescribed limits. The In vitro drug release study indicates that formulation PCF-7 containing EC, HPMC K100M in 1:2 ratio shown good release pattern for 14 hours compares to other formulations. The short-term stability study proved no change in the formulation of ageing and it indicates good stability. Seller Inventory # 9786138387824

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Rajan Kothari|Gaurav Kumar Sharma|Pankaj Chasta Atul Tiwari
Published by LAP LAMBERT Academic Publishing, 2018
ISBN 10: 6138387821 ISBN 13: 9786138387824
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Kothari RajanMr. Rajan Kothari, M.Pharm.(Pharmaceutics), Rajiv Gandhi University of Health Sciences, Bangalore, Karnataka, India. Assistant Professor at Faculty of Pharmaceutical Sciences, Mewar University, Gangrar, Chittorgarh-31290. Seller Inventory # 385848205

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Kothari, Rajan/ Sharma, Gaurav Kumar/ Atul Tiwari, Pankaj Chasta
Published by LAP LAMBERT Academic Publishing, 2018
ISBN 10: 6138387821 ISBN 13: 9786138387824
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Paperback. Condition: Brand New. 76 pages. 8.66x5.91x0.18 inches. In Stock. Seller Inventory # zk6138387821

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Rajan Kothari
ISBN 10: 6138387821 ISBN 13: 9786138387824
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Taschenbuch. Condition: Neu. Neuware -In the present study, we have prepared matrix tablet formulations using Prazocin as a model drug and Ethyl Cellulose, Two grades of Hydroxy Propyl Methyl Cellulose- HPMC-K4M & HPMC-K100M as polymers in different ratios. The developed matrix tablets were evaluated for different physical-chemical evaluations like drug content, hardness, friability, swelling index etc. All the formulations had shown the results within prescribed limits. The In vitro drug release study indicates that formulation PCF-7 containing EC, HPMC K100M in 1:2 ratio shown good release pattern for 14 hours compares to other formulations. The short-term stability study proved no change in the formulation of ageing and it indicates good stability.Books on Demand GmbH, Überseering 33, 22297 Hamburg 76 pp. Englisch. Seller Inventory # 9786138387824

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