Drebrin: From Structure and Function to Physiological and Pathological Roles: 1006 (Advances in Experimental Medicine and Biology, 1006) - Hardcover

Book 308 of 544: Advances in Experimental Medicine and Biology
 
9784431565482: Drebrin: From Structure and Function to Physiological and Pathological Roles: 1006 (Advances in Experimental Medicine and Biology, 1006)
Hardcover
ISBN 10: 4431565485 ISBN 13: 9784431565482
Publisher: Springer, 2017

Synopsis

This book is the first comprehensive review of drebrin, which plays pivotal roles in various cellular events, via forming unique actin cytoskeletons, including synapse formation and in synaptic function. Particularly the loss of drebrin from dendritic spines is used as a marker of dementia in neurological disorders such as Alzheimer’s disease. Since drebrin was first identified by our group in 1985, many studies of drebrin have been done in various fields, including not only molecular biology, biophysics, cell biology, neuroscience, clinical studies, spermatogenesis, immunology, and cancer metastasis, but others as well. The structure of this book facilitates the understanding of the whole picture of studies on drebrin. The volume begins with a general introduction to drebrin, and then the chapters in the second part provide the basic knowledge for further understanding. The third part examines its function in the nervous system, and the fourth part discusses its function in the non-nervous system. This work will appeal to researchers who are interested in cytoskeletal dynamics at membrane-cytoskeletal interface as well as the number of them who use drebrin as a tool, such as a marker of synaptic function or a disease marker. This volume is kept as concise as possible in order to be understood by readers in diverse scientific disciplines.

"synopsis" may belong to another edition of this title.

About the Author

Tomoaki Shirao, MD, PhD
Department of Neurobiology and Behavior
Gunma University Graduate School of Medicine
Gunma, Japan

Yuko Sekino, PhD
Division of Pharmacology
National Institute of Health Sciences
Tokyo, Japan

From the Back Cover

This book is the first comprehensive review of drebrin, which plays pivotal roles in various cellular events, via forming unique actin cytoskeletons, including synapse formation and in synaptic function. Particularly the loss of drebrin from dendritic spines is used as a marker of dementia in neurological disorders such as Alzheimer’s disease. Since drebrin was first identified by our group in 1985, many studies of drebrin have been done in various fields, including not only molecular biology, biophysics, cell biology, neuroscience, clinical studies, spermatogenesis, immunology, and cancer metastasis, but others as well. The structure of this book facilitates the understanding of the whole picture of studies on drebrin. The volume begins with a general introduction to drebrin, and then the chapters in the second part provide the basic knowledge for further understanding. The third part examines its function in the nervous system, and the fourth part discusses its function in the non-nervous system. This work will appeal to researchers who are interested in cytoskeletal dynamics at membrane-cytoskeletal interface as well as the number of them who use drebrin as a tool, such as a marker of synaptic function or a disease marker. This volume is kept as concise as possible in order to be understood by readers in diverse scientific disciplines.

"About this title" may belong to another edition of this title.

Publisher
Springer
Publication date
2017
Language
English
ISBN 10 
4431565485
ISBN 13 
9784431565482
Binding
Hardcover
Edition number
1
Number of pages
413
Editor
Shirao Tomoaki, Sekino Yuko

Other Popular Editions of the Same Title

9784431568179: Drebrin: From Structure and Function to Physiological and Pathological Roles: 1006 (Advances in Experimental Medicine and Biology, 1006)

Featured Edition

ISBN 10:  4431568174 ISBN 13:  9784431568179
Publisher: Springer, 2018
Softcover