Microbial Production: From Genome Design to Cell Engineering - Hardcover

Hardcover

ISBN 10: 4431546065 ISBN 13: 9784431546061

Publisher: Springer, 2014

Synopsis

Microbial production: From genome design to cell surface engineering affords a comprehensive review of novel technology and approaches being implemented for manufacturing microorganisms, written by specialists in both academia and industry. This book is divided into three sections: the first includes technology for improvement of fermentation strains and many supporting technologies and information; the second examines novel technology useful for analysis of cell activities, analyzing gene function, and designing genomes of producer strains; and finally, a discussion of the practical application of the techniques and success case studies in many fields of bio-production, such as microbiological production, pharmaceuticals, chemicals, foods and cosmetics.

About this title

About the Author

Hideharu Anazawa, Ph.D., Director, Japan Bioindustry Association

Sakayu Shimizu, Ph.D., Professor, Kyoto Gakuen University

From the Back Cover

In this book the reader will find an introduction and review of recent research and development of the technology for bio-production of manufacturing microorganisms, a field in which Japan leads the world. Presented here are novel concepts and technology for breeding fermentation strains as well as the analytical methodology for gene function and genome design of producer strains.

Successful results are shown in diverse fields of application such as microbiological production, pharmaceuticals, chemicals, foods, and cosmetics. Two methodologies announced in the twenty-first century have dramatically improved the productivity of fermentation strains. One is a method of synthesizing the entire genome of the fermentation strain as proposed by Venter, famous for his work in human genome sequencing. Another is the minimum genome factory, which provides the basis for breeding a strain whose genome optimizes production of the target material.

Each chapter has been written by specialists in academia or by active researchers in industry, creating a work that is informative for researchers interested in the industrialization of novel concepts or technologies by a microbial production system. The book consists of three parts. The first presents the innovative concepts and technology for improvement of the fermentation strain, with supporting technology and other information. The second describes novel technologies useful for analysis of cell activities, and the third provides practical applications of those technologies and success stories for microbial production.

Edition details

• Publisher: Springer
• Publication date: 2014
• Language: English
• ISBN 10: 4431546065
• ISBN 13: 9784431546061
• Binding: Hardcover
• Number of pages: 315
• Editor: Anazawa Hideharu, Shimizu Sakayu