Activated Nitriles in Heterocyclic Synthesis: Studies on the Chemistry of N-(cyanoacetyl) aminoantipyrine & antipyrinylhydrazonomalononitrile - Softcover

Ahmed, Ramy Rabie Shafek; Fadda, A; Bondock

Softcover

ISBN 10: 384848787X ISBN 13: 9783848487875

Publisher: LAP LAMBERT Academic Publishing, 2012

Synopsis

The introduction part in this work presents a systematic and comprehensive survey of the methods of preparation and the chemical reactivity of cyanoacetamide derivatives. These compounds are important intermediates for the synthesis of a variety of otherwise difficulty accessible, synthetically useful and novel heterocyclic systems, for this reason. We focused our aim to use starting material possess a wide variety of potentially useful applications including biological, clinical and pharmacological areas. We found 4-aminoantipyrine (4AAP) possess the previously mentioned properties, so we used it as precursor to prepare polyfunctionally substituted heterocyclic compounds. The work divided into two parts, the first part discussed the utilization of N-(cyanoacetyl) aminoantipyrine for building new heterocyclic compounds. The second part discussed the formation of novel heterocyclic rings via the use of antipyrinylhydrazonomalononitrile as starting material. Both two parts followed by antimicrobial screening for the selected prepared compounds.

About this title

About the Author

Ramy Rabie has obtained his Master Degree in Organic Chemistry in 2008 Mansoura, Egypt. He has worked in different fields of Chemistry (Egyptian Armed Force-Chemical War 2003-05),(Instructor of Chemistry- Mansoura University 2005-08),(Chemist in the Central Lab.of Dakahlia Water Company 2003-10). In 2010 he joined the SEGAS Lab Staff until now.

Edition details

• Publisher: LAP LAMBERT Academic Publishing
• Publication date: 2012
• Language: English
• ISBN 10: 384848787X
• ISBN 13: 9783848487875
• Binding: Paperback
• Number of pages: 188