Formulation and Evaluation of Cephalexin Extended Release Tablet: Comparatively Study with Marketed Formulations - Softcover

Sharma, Hemendra Kumar; Chaurasia, Sandhya; Vasireddy, Suneel Kumar

Softcover

ISBN 10: 3848432633 ISBN 13: 9783848432639

Publisher: LAP LAMBERT Academic Publishing, 2012

Synopsis

In this study, controlled release matrix tablets containing cephelexin were prepared using HPMC15 cps and Eudragit L100 in different concentration by Direct compression method. Tablets were evaluated for physical properties,Hardness, friability, weight variation and In vitro dissolution study was carried on USP II apparetus (peddle type). The best formulations selected based on above parameters were subjected for Extend release study with use of different ratio of polymer as Eudragit and HPMC .The tablets with Eudragit were found to release drug for longer duration of time as compared to formulations containing HPMC. The drug release from the tablets was sufficiently sustained.

About this title

About the Author

Mr. Hemendra Kumar Sharma has obtained M. Pharm degree in Pharmaceutical Chemistry in 2011. Since he has published three international and ten national research article in reputed journals in field of analysis and he has also obtained scientific credit from international journal.

Edition details

• Publisher: LAP LAMBERT Academic Publishing
• Publication date: 2012
• Language: English
• ISBN 10: 3848432633
• ISBN 13: 9783848432639
• Binding: Paperback
• Number of pages: 144