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Analysis of Some Phosphorus Containing Compounds in Pharmaceuticals: Analytical Determination of Alendronate, Etidronate and Risedronate in Drug Substance and Pharmaceutical Preparations - Softcover
Synopsis
Among phosphorus containing pharmaceutical compounds, bisphosphonates is a very important class. Therapeutic uses of bisphosphonates include maagement of malignancy-associated hypercalcemia, treatment of postmenopausal osteoporosis and cancer. Bisphosphonates, as a group of active pharmaceutical compounds, generally "give headache" to analytical chemists. The two phosphonic groups per molecule lend a strongly ionic character and increased polarity to these compounds. Additionally, the majority of the members of this family lacks of chromophores, or even has a weak one, excluding convenient sensitive UV or fluorescence detection.This work is devoted to the determination of three bisphosphonate drugs commercially available in the local Egyptian market (alendronate, etidronate and risedronate.The usefulness of different spectrophotometric and chromatographic methods was exploited.The proposed methods are of great value in quality control analysis of the studied compounds owing to their improved simplicity, sensitivity, low-cost, and its independence on expensive instruments, or critical analytical reagents.
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About the Author
Dr. Rania El-Shaheny is a lecturer in Department of Analytical chemistry, Faculty of Pharmacy, Mansoura University, Egypt. She received MSc and PhD in Analytical Chemistry from Fcaulty of Pharmacy, Mansoura University. Her research interests include pharmaceutical analysis, quality control, stability studies of drugs and therapeutic drug monitoring.
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Analysis of Some Phosphorus Containing Compounds in Pharmaceuticals
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LAP LAMBERT Academic Publishing, 2012
ISBN 10: 3848422751
ISBN 13: 9783848422753
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Kartoniert / Broschiert. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: El-Shaheny RaniaDr. Rania El-Shaheny is a lecturer in Department of Analytical chemistry, Faculty of Pharmacy, Mansoura University, Egypt. She received MSc and PhD in Analytical Chemistry from Fcaulty of Pharmacy, Mansoura University. Seller Inventory # 5521079
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Analysis of Some Phosphorus Containing Compounds in Pharmaceuticals : Analytical Determination of Alendronate, Etidronate and Risedronate in Drug Substance and Pharmaceutical Preparations
Published by
LAP Lambert Academic Publishing, 2012
ISBN 10: 3848422751
ISBN 13: 9783848422753
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Among phosphorus containing pharmaceutical compounds, bisphosphonates is a very important class. Therapeutic uses of bisphosphonates include maagement of malignancy-associated hypercalcemia, treatment of postmenopausal osteoporosis and cancer. Bisphosphonates, as a group of active pharmaceutical compounds, generally 'give headache' to analytical chemists. The two phosphonic groups per molecule lend a strongly ionic character and increased polarity to these compounds. Additionally, the majority of the members of this family lacks of chromophores, or even has a weak one, excluding convenient sensitive UV or fluorescence detection.This work is devoted to the determination of three bisphosphonate drugs commercially available in the local Egyptian market (alendronate, etidronate and risedronate.The usefulness of different spectrophotometric and chromatographic methods was exploited.The proposed methods are of great value in quality control analysis of the studied compounds owing to their improved simplicity, sensitivity, low-cost, and its independence on expensive instruments, or critical analytical reagents. Seller Inventory # 9783848422753
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Analysis of Some Phosphorus Containing Compounds in Pharmaceuticals | Analytical Determination of Alendronate, Etidronate and Risedronate in Drug Substance and Pharmaceutical Preparations
Published by
LAP Lambert Academic Publishing, 2012
ISBN 10: 3848422751
ISBN 13: 9783848422753
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Taschenbuch. Condition: Neu. Analysis of Some Phosphorus Containing Compounds in Pharmaceuticals | Analytical Determination of Alendronate, Etidronate and Risedronate in Drug Substance and Pharmaceutical Preparations | Rania El-Shaheny (u. a.) | Taschenbuch | Englisch | LAP Lambert Academic Publishing | EAN 9783848422753 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Seller Inventory # 106587356
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Analysis of Some Phosphorus Containing Compounds in Pharmaceuticals: Analytical Determination of Alendronate, Etidronate and Risedronate in Drug Substance and Pharmaceutical Preparations
Published by
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ISBN 10: 3848422751
ISBN 13: 9783848422753
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