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Method Development of Acarbose As API and Tablet Dosage Form.: Method Development of Acarbose as API & Tablet Dosage Form By UV-Vis Spectrophotometer - Softcover
Synopsis
A simple rapid spectrophotometeric method has been developed for estimation of acarbose from bulk drug and tablet dosage form by using potassium permagnate and sodium hydroxide as oxidizing agent. The method is based on the formation of green colored complex of drug with 0.1 N alkaline potassium permanganate having absorbance maxima at 625 nm. The beer’s law is obeyed in the concentration range of 10-70 µg/ml of the drug but more precisely it obeys in the range of 10-50 µg/ml. The slope and intercept values are 0.0118 and 0.0071, respectively. Results of analysis of this method were validated statistically and by recovery studies. The method is applied to the marketed tablet formulation. Result of analysis of tablet formation given as percentage of label claim+ standard deviation is 99.78 + 0.1053. The precision and accuracy was examined by performing recovery studies and was found to be 99.59 + 0.180.The developed method is simple, sensitive and reproducible and can be used for routine analysis of acarbose from bulk and tablet dosage form.
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About the Author
Dr. Ganesh Kumar Bhatt, Assistant Professor, Division of Pharmaceutical Sciences, Shri Guru Ram Rai Institute of Technology & Science, Dehradun, Uttarakhand,INDIA. published 13 research papers in various international & national scientific journals and presented number of research papers in national conferences.
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Method Development of Acarbose As API and Tablet Dosage Form.
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LAP LAMBERT Academic Publishing Dez 2011, 2011
ISBN 10: 3846599654
ISBN 13: 9783846599655
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A simple rapid spectrophotometeric method has been developed for estimation of acarbose from bulk drug and tablet dosage form by using potassium permagnate and sodium hydroxide as oxidizing agent. The method is based on the formation of green colored complex of drug with 0.1 N alkaline potassium permanganate having absorbance maxima at 625 nm. The beer s law is obeyed in the concentration range of 10-70 µg/ml of the drug but more precisely it obeys in the range of 10-50 µg/ml. The slope and intercept values are 0.0118 and 0.0071, respectively. Results of analysis of this method were validated statistically and by recovery studies. The method is applied to the marketed tablet formulation. Result of analysis of tablet formation given as percentage of label claim+ standard deviation is 99.78 + 0.1053. The precision and accuracy was examined by performing recovery studies and was found to be 99.59 + 0.180.The developed method is simple, sensitive and reproducible and can be used for routine analysis of acarbose from bulk and tablet dosage form. 56 pp. Englisch. Seller Inventory # 9783846599655
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Method Development of Acarbose As API and Tablet Dosage Form. : Method Development of Acarbose as API & Tablet Dosage Form By UV-Vis Spectrophotometer
Published by
LAP LAMBERT Academic Publishing, 2011
ISBN 10: 3846599654
ISBN 13: 9783846599655
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Taschenbuch
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - A simple rapid spectrophotometeric method has been developed for estimation of acarbose from bulk drug and tablet dosage form by using potassium permagnate and sodium hydroxide as oxidizing agent. The method is based on the formation of green colored complex of drug with 0.1 N alkaline potassium permanganate having absorbance maxima at 625 nm. The beer s law is obeyed in the concentration range of 10-70 µg/ml of the drug but more precisely it obeys in the range of 10-50 µg/ml. The slope and intercept values are 0.0118 and 0.0071, respectively. Results of analysis of this method were validated statistically and by recovery studies. The method is applied to the marketed tablet formulation. Result of analysis of tablet formation given as percentage of label claim+ standard deviation is 99.78 + 0.1053. The precision and accuracy was examined by performing recovery studies and was found to be 99.59 + 0.180.The developed method is simple, sensitive and reproducible and can be used for routine analysis of acarbose from bulk and tablet dosage form. Seller Inventory # 9783846599655
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Method Development of Acarbose As API and Tablet Dosage Form.
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Editorial Academica Espanola, 2011
ISBN 10: 3846599654
ISBN 13: 9783846599655
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Method Development of Acarbose As API and Tablet Dosage Form.
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LAP LAMBERT Academic Publishing, 2011
ISBN 10: 3846599654
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Kumar GaneshDr. Ganesh Kumar Bhatt, Assistant Professor, Division of Pharmaceutical Sciences, Shri Guru Ram Rai Institute of Technology & Science, Dehradun, Uttarakhand,INDIA. published 13 research papers in various international & n. Seller Inventory # 5502365
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Method Development of Acarbose As API and Tablet Dosage Form.
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Method Development of Acarbose As API and Tablet Dosage Form.
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Editorial Academica Espanola, 2011
ISBN 10: 3846599654
ISBN 13: 9783846599655
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Method Development of Acarbose As API and Tablet Dosage Form.
Published by
LAP LAMBERT Academic Publishing Dez 2011, 2011
ISBN 10: 3846599654
ISBN 13: 9783846599655
New
Taschenbuch
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -A simple rapid spectrophotometeric method has been developed for estimation of acarbose from bulk drug and tablet dosage form by using potassium permagnate and sodium hydroxide as oxidizing agent. The method is based on the formation of green colored complex of drug with 0.1 N alkaline potassium permanganate having absorbance maxima at 625 nm. The beer's law is obeyed in the concentration range of 10-70 µg/ml of the drug but more precisely it obeys in the range of 10-50 µg/ml. The slope and intercept values are 0.0118 and 0.0071, respectively. Results of analysis of this method were validated statistically and by recovery studies. The method is applied to the marketed tablet formulation. Result of analysis of tablet formation given as percentage of label claim+ standard deviation is 99.78 + 0.1053. The precision and accuracy was examined by performing recovery studies and was found to be 99.59 + 0.180.The developed method is simple, sensitive and reproducible and can be used for routine analysis of acarbose from bulk and tablet dosage form.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 56 pp. Englisch. Seller Inventory # 9783846599655
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Method Development of Acarbose As API and Tablet Dosage Form. | Method Development of Acarbose as API & Tablet Dosage Form By UV-Vis Spectrophotometer
Published by
LAP LAMBERT Academic Publishing, 2011
ISBN 10: 3846599654
ISBN 13: 9783846599655
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Taschenbuch
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Taschenbuch. Condition: Neu. Method Development of Acarbose As API and Tablet Dosage Form. | Method Development of Acarbose as API & Tablet Dosage Form By UV-Vis Spectrophotometer | Ganesh Kumar | Taschenbuch | 56 S. | Englisch | 2011 | LAP LAMBERT Academic Publishing | EAN 9783846599655 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Seller Inventory # 106702649