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DNA Content Analysis and Invitro Cytotoxicity in Bladder Cancer Patients: Flow Cytometric Evaluation of DNA Content Analysis and Therapeutic Responses ... of Transitional Cell Carcinoma Patients - Softcover
Synopsis
Transitional Cell Carcinoma accounts for more than 90% of bladder cancer. DNA analysis is the second most important application of flow cytometry. DNA content of individual cells give information about their ploidy in tumours and the distribution of cells across the cell cycle. Tumor DNA content has been found to be of prognostic importance for patients with many malignant tumors, such as carcinoma of urinary bladder. In-vitro cytotoxic studies on patients own cultured tumor tissue cells was done for the optimum cytotoxic combination of chemotherapeutic drugs and immunomodulators. This study was proposed investigate the DNA content evaluation and invitro monitoring of cytotoxicity produced by various chemotherapeutic agents viz Doxorubicin, Mitomycin C and Cisplatin on cultured cancer cells of patients having superficial TCC, individually as well as in combination of immunomodulating agents BCG and interferon alpha- 2b.Out of 25 samples nine were were aneuploid, one diploid and one tetraploid.Grade II samples were 70%. Out of 22 samples on which cytotoxicity test performed, 36.4% showed maximum cytotoxicity to the combination therapy and 5 showed to BCG drug.
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About the Author
The author has completed his PhD from Central Drug Research Institute,India and then joined esteemed All India Institute of Medical Sciences, Delhi,India. He is now working as senior scientist in Indian Council of Medical Research,India .He has 15 research papers to his credit,and has been Guide and co-guide to one PhD,7 MSc and 2 DNB students.
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DNA Content Analysis and Invitro Cytotoxicity in Bladder Cancer Patients
Published by
LAP LAMBERT Academic Publishing Nov 2010, 2010
ISBN 10: 3843364133
ISBN 13: 9783843364133
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Transitional Cell Carcinoma accounts for more than 90% of bladder cancer. DNA analysis is the second most important application of flow cytometry. DNA content of individual cells give information about their ploidy in tumours and the distribution of cells across the cell cycle. Tumor DNA content has been found to be of prognostic importance for patients with many malignant tumors, such as carcinoma of urinary bladder. In-vitro cytotoxic studies on patients own cultured tumor tissue cells was done for the optimum cytotoxic combination of chemotherapeutic drugs and immunomodulators. This study was proposed investigate the DNA content evaluation and invitro monitoring of cytotoxicity produced by various chemotherapeutic agents viz Doxorubicin, Mitomycin C and Cisplatin on cultured cancer cells of patients having superficial TCC, individually as well as in combination of immunomodulating agents BCG and interferon alpha- 2b.Out of 25 samples nine were were aneuploid, one diploid and one tetraploid.Grade II samples were 70%. Out of 22 samples on which cytotoxicity test performed, 36.4% showed maximum cytotoxicity to the combination therapy and 5 showed to BCG drug. 80 pp. Englisch. Seller Inventory # 9783843364133
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DNA Content Analysis and Invitro Cytotoxicity in Bladder Cancer Patients
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VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG, 2010
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DNA Content Analysis and Invitro Cytotoxicity in Bladder Cancer Patients
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VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG, 2010
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DNA Content Analysis and Invitro Cytotoxicity in Bladder Cancer Patients
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Varma SaurabhThe author has completed his PhD from Central Drug Research Institute,India and then joined esteemed All India Institute of Medical Sciences, Delhi,India. He is now working as senior scientist in Indian Council of Medica. Seller Inventory # 5466364
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DNA Content Analysis and Invitro Cytotoxicity in Bladder Cancer Patients
Published by
VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG, 2010
ISBN 10: 3843364133
ISBN 13: 9783843364133
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Softcover
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DNA Content Analysis and Invitro Cytotoxicity in Bladder Cancer Patients
Published by
LAP LAMBERT Academic Publishing Nov 2010, 2010
ISBN 10: 3843364133
ISBN 13: 9783843364133
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Taschenbuch
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Transitional Cell Carcinoma accounts for more than 90% of bladder cancer. DNA analysis is the second most important application of flow cytometry. DNA content of individual cells give information about their ploidy in tumours and the distribution of cells across the cell cycle. Tumor DNA content has been found to be of prognostic importance for patients with many malignant tumors, such as carcinoma of urinary bladder. In-vitro cytotoxic studies on patients own cultured tumor tissue cells was done for the optimum cytotoxic combination of chemotherapeutic drugs and immunomodulators. This study was proposed investigate the DNA content evaluation and invitro monitoring of cytotoxicity produced by various chemotherapeutic agents viz Doxorubicin, Mitomycin C and Cisplatin on cultured cancer cells of patients having superficial TCC, individually as well as in combination of immunomodulating agents BCG and interferon alpha- 2b.Out of 25 samples nine were were aneuploid, one diploid and one tetraploid.Grade II samples were 70%. Out of 22 samples on which cytotoxicity test performed, 36.4% showed maximum cytotoxicity to the combination therapy and 5 showed to BCG drug.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 80 pp. Englisch. Seller Inventory # 9783843364133
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DNA Content Analysis and Invitro Cytotoxicity in Bladder Cancer Patients : Flow Cytometric Evaluation of DNA Content Analysis and Therapeutic Responses (Invitro Cytotoxicity) of Transitional Cell Carcinoma Patients
Published by
LAP LAMBERT Academic Publishing, 2010
ISBN 10: 3843364133
ISBN 13: 9783843364133
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Transitional Cell Carcinoma accounts for more than 90% of bladder cancer. DNA analysis is the second most important application of flow cytometry. DNA content of individual cells give information about their ploidy in tumours and the distribution of cells across the cell cycle. Tumor DNA content has been found to be of prognostic importance for patients with many malignant tumors, such as carcinoma of urinary bladder. In-vitro cytotoxic studies on patients own cultured tumor tissue cells was done for the optimum cytotoxic combination of chemotherapeutic drugs and immunomodulators. This study was proposed investigate the DNA content evaluation and invitro monitoring of cytotoxicity produced by various chemotherapeutic agents viz Doxorubicin, Mitomycin C and Cisplatin on cultured cancer cells of patients having superficial TCC, individually as well as in combination of immunomodulating agents BCG and interferon alpha- 2b.Out of 25 samples nine were were aneuploid, one diploid and one tetraploid.Grade II samples were 70%. Out of 22 samples on which cytotoxicity test performed, 36.4% showed maximum cytotoxicity to the combination therapy and 5 showed to BCG drug. Seller Inventory # 9783843364133
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DNA Content Analysis and Invitro Cytotoxicity in Bladder Cancer Patients | Flow Cytometric Evaluation of DNA Content Analysis and Therapeutic Responses (Invitro Cytotoxicity) of Transitional Cell Carcinoma Patients
Published by
LAP LAMBERT Academic Publishing, 2010
ISBN 10: 3843364133
ISBN 13: 9783843364133
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Taschenbuch
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Taschenbuch. Condition: Neu. DNA Content Analysis and Invitro Cytotoxicity in Bladder Cancer Patients | Flow Cytometric Evaluation of DNA Content Analysis and Therapeutic Responses (Invitro Cytotoxicity) of Transitional Cell Carcinoma Patients | Saurabh Varma | Taschenbuch | 80 S. | Englisch | 2010 | LAP LAMBERT Academic Publishing | EAN 9783843364133 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Seller Inventory # 107225784