Interaction of proteins is central to various cellular processes like cell growth, proliferation, differentiation and programmed cell death. To study the specific role of a single protein-protein interaction of a multifunctional protein or protein complex, it is necessary to interrupt each single interaction individually to elucidate their respective role and influence they exert. In this study two approaches were employed to modulate protein interactions. First one was to target a known protein-protein interaction by expressing specific peptides in vivo. The second one was based on the LXXLL motif to disrupt interactions between transcription factors and coactivators.
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Altaf A Dar is currently working on identifying biomarkers involved in melanoma progression and metastasis at CPMC, San Francisco, CA. Previously Dr. Dar worked on gastric cancer at Vanderbilt University, Nashville, TN. Dr. Dar earned his PhD from Friedrich Schiller University, Jena Germany, where he worked on protein-protein interactions.
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Dar AltafAltaf A Dar is currently working on identifying biomarkers involved in melanoma progression and metastasis at CPMC, San Francisco, CA. Previously Dr. Dar worked on gastric cancer at Vanderbilt University, Nashville, TN. Dr. . Seller Inventory # 5466141
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Interaction of proteins is central to various cellular processes like cell growth, proliferation, differentiation and programmed cell death. To study the specific role of a single protein-protein interaction of a multifunctional protein or protein complex, it is necessary to interrupt each single interaction individually to elucidate their respective role and influence they exert. In this study two approaches were employed to modulate protein interactions. First one was to target a known protein-protein interaction by expressing specific peptides in vivo. The second one was based on the LXXLL motif to disrupt interactions between transcription factors and coactivators.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 96 pp. Englisch. Seller Inventory # 9783843361781
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Taschenbuch. Condition: Neu. Modulation of protein-protein interactions | The role of short peptides in modulating protein-protein interactions in-vivo | Altaf Dar | Taschenbuch | 96 S. | Englisch | 2010 | LAP LAMBERT Academic Publishing | EAN 9783843361781 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Seller Inventory # 107263909