Biomechanical Engineering of Endothelial Cells: Microcontact Printing Approaches to Pattern Endothelial Cell Attachment on Silicone Microgrooves - Softcover

Roy, Dheeraj; Barbee, Kenneth

Softcover

ISBN 10: 3838395921 ISBN 13: 9783838395920

Publisher: LAP LAMBERT Academic Publishing, 2010

Synopsis

Shape-dependent endothelial cell properties that are independent of fluid shear stress remain largely undefined. More recently, surface micropatterning has been investigated as an approach to control the morphology and orientation of endothelial cells using synthetic substratum. Most research studies have reported the effects of microtopography on sub-confluent layers of cells, which has been the standard in research investigations to date. In this book, surface micropatterning is used to mimic the natural endothelial cell vasculature in confluent layers. Substrates with patterned microgrooves provide a method for evaluating the interplay between cell orientation and spatial localization of membrane proteins, which may be patterned using microcontact printing techniques.

About this title

About the Author

Dheeraj Roy, M.S. - Studied Biomedical Engineering at Drexel University with a minor in Business Administration. Research Assistant at Harvard Medical School, Boston.

Edition details

• Publisher: LAP LAMBERT Academic Publishing
• Publication date: 2010
• Language: English
• ISBN 10: 3838395921
• ISBN 13: 9783838395920
• Binding: Paperback
• Number of pages: 96