Microsponge Based Colonic Drug Delivery Systems: Development and Characterization of Microsponge Based Colonic Drug Delivery Systems - Softcover
Synopsis
This study encompasses preparation microsponges based colon specific tablet formulations. Initially, microsponges of dicyclomine and paracetamol were prepared by quasi-emulsion solvent diffusion method. The reason for preparing microsponge due to the fact that, drug carrier systems less than 200 ?m may efficiently be taken up by the macrophages present in colon tissue, thus exhibit effective localized drug action at the desired site. A subsequent increase of residence time that may be postulated for microsponges as compared to existing drug delivery systems may allow dose reduction and enhance therapeutic effect. Another reason for preparing microsponges was their sponge like texture that can easily be compressed by direct compression for producing mechanically strong tablets. Then core tablets of microsponges were prepared by direct compression method and were compression coated with pectin:HPMC mixture. The reason for selecting pectin was its biodegradation in the colon by colonic flora. HPMC is reported to increase the mechanical strength of the tablet coat and helped in maintaining its integrity during its sojourn in the gastro-intestinal tract.
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About the Author
Dr. Vikas Jain obtained his Ph.D. in 2010 from Shobhit University, Meerut, Uttar Pradesh, India. He has more than 07 publications to his credit in journals of repute and many presentations in International and National Conferences. Dr. Jain has contributed immensely in the field of Microsponge based Novel Drug Delivery Systems.
Dr. Vikas Jain obtained his Ph.D. in 2010 from Shobhit University, Meerut, Uttar Pradesh, India. He has more than 07 publications to his credit in journals of repute and many presentations in International and National Conferences. Dr. Jain has contributed immensely in the field of Microsponge based Novel Drug Delivery Systems.
"About this title" may belong to another edition of this title.
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Microsponge Based Colonic Drug Delivery Systems
Published by
LAP LAMBERT Academic Publishing Okt 2010, 2010
ISBN 10: 3838394178
ISBN 13: 9783838394176
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This study encompasses preparation microsponges based colon specific tablet formulations. Initially, microsponges of dicyclomine and paracetamol were prepared by quasi-emulsion solvent diffusion method. The reason for preparing microsponge due to the fact that, drug carrier systems less than 200 m may efficiently be taken up by the macrophages present in colon tissue, thus exhibit effective localized drug action at the desired site. A subsequent increase of residence time that may be postulated for microsponges as compared to existing drug delivery systems may allow dose reduction and enhance therapeutic effect. Another reason for preparing microsponges was their sponge like texture that can easily be compressed by direct compression for producing mechanically strong tablets. Then core tablets of microsponges were prepared by direct compression method and were compression coated with pectin:HPMC mixture. The reason for selecting pectin was its biodegradation in the colon by colonic flora. HPMC is reported to increase the mechanical strength of the tablet coat and helped in maintaining its integrity during its sojourn in the gastro-intestinal tract. 132 pp. Englisch. Seller Inventory # 9783838394176
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Microsponge Based Colonic Drug Delivery Systems
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Microsponge Based Colonic Drug Delivery Systems
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Kartoniert / Broschiert. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Jain VikasDr. Vikas Jain obtained his Ph.D. in 2010 from Shobhit University, Meerut, Uttar Pradesh, India. He has more than 07 publications to his credit in journals of repute and many presentations in International and National Conf. Seller Inventory # 5419642
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Microsponge Based Colonic Drug Delivery Systems
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ISBN 13: 9783838394176
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Microsponge Based Colonic Drug Delivery Systems
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VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG, 2010
ISBN 10: 3838394178
ISBN 13: 9783838394176
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Microsponge Based Colonic Drug Delivery Systems
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ISBN 10: 3838394178
ISBN 13: 9783838394176
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This study encompasses preparation microsponges based colon specific tablet formulations. Initially, microsponges of dicyclomine and paracetamol were prepared by quasi-emulsion solvent diffusion method. The reason for preparing microsponge due to the fact that, drug carrier systems less than 200 ¿m may efficiently be taken up by the macrophages present in colon tissue, thus exhibit effective localized drug action at the desired site. A subsequent increase of residence time that may be postulated for microsponges as compared to existing drug delivery systems may allow dose reduction and enhance therapeutic effect. Another reason for preparing microsponges was their sponge like texture that can easily be compressed by direct compression for producing mechanically strong tablets. Then core tablets of microsponges were prepared by direct compression method and were compression coated with pectin:HPMC mixture. The reason for selecting pectin was its biodegradation in the colon by colonic flora. HPMC is reported to increase the mechanical strength of the tablet coat and helped in maintaining its integrity during its sojourn in the gastro-intestinal tract.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 132 pp. Englisch. Seller Inventory # 9783838394176
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Microsponge Based Colonic Drug Delivery Systems : Development and Characterization of Microsponge Based Colonic Drug Delivery Systems
Published by
LAP LAMBERT Academic Publishing, 2010
ISBN 10: 3838394178
ISBN 13: 9783838394176
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - This study encompasses preparation microsponges based colon specific tablet formulations. Initially, microsponges of dicyclomine and paracetamol were prepared by quasi-emulsion solvent diffusion method. The reason for preparing microsponge due to the fact that, drug carrier systems less than 200 m may efficiently be taken up by the macrophages present in colon tissue, thus exhibit effective localized drug action at the desired site. A subsequent increase of residence time that may be postulated for microsponges as compared to existing drug delivery systems may allow dose reduction and enhance therapeutic effect. Another reason for preparing microsponges was their sponge like texture that can easily be compressed by direct compression for producing mechanically strong tablets. Then core tablets of microsponges were prepared by direct compression method and were compression coated with pectin:HPMC mixture. The reason for selecting pectin was its biodegradation in the colon by colonic flora. HPMC is reported to increase the mechanical strength of the tablet coat and helped in maintaining its integrity during its sojourn in the gastro-intestinal tract. Seller Inventory # 9783838394176
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Microsponge Based Colonic Drug Delivery Systems | Development and Characterization of Microsponge Based Colonic Drug Delivery Systems
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Taschenbuch. Condition: Neu. Microsponge Based Colonic Drug Delivery Systems | Development and Characterization of Microsponge Based Colonic Drug Delivery Systems | Vikas Jain (u. a.) | Taschenbuch | 132 S. | Englisch | 2010 | LAP LAMBERT Academic Publishing | EAN 9783838394176 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Seller Inventory # 107266239
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Microsponge Based Colonic Drug Delivery Systems: Development and Characterization of Microsponge Based Colonic Drug Delivery Systems
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ISBN 13: 9783838394176
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