Computational Models of Spike-Timing Dependent Plasticity:: Synapses, Neurons and Circuits - Softcover

Zou, Quan

Softcover

ISBN 10: 3838315278 ISBN 13: 9783838315270

Publisher: LAP LAMBERT Academic Publishing, 2009

Synopsis

This thesis work consists in a theoretical and computational study of a recently-indentified type of synaptic plasticity, called "spike-timing dependent plasticity" (STDP). The thesis is articulated in three main parts. (1) A phenomenological model of STDP is introduced based on experimental data, and the biophysical plausibility of this model is analyzed. ­(2) This model is then implemented in an analog-neuron simulator, in which neurons are emulated by integrated circuits (ASICs). The behavior of elementary circuits of neurons interconnected with STDP synapses is analyzed and compared to the results of numerical simulations. (3) STDP is studied numerically at the cellular level in conditions of multiple and complex synaptic input. In conclusion, both numerical and analog simulations suggest that STDP is optimal to detect and process correlations among synaptic inputs.

About this title

About the Author

Dr. Zou studies mathematical models of adapted learning theory. He obtained his PhD from the University of Paris VI with Professor Alain Destexhe as adviser. He is a member of Society for Neuroscience, Society for Industrial and Applied Mathematics, and the American Mathematical Society. He also serves as reviewer for various academic journals.

Edition details

• Publisher: LAP LAMBERT Academic Publishing
• Publication date: 2009
• Language: English
• ISBN 10: 3838315278
• ISBN 13: 9783838315270
• Binding: Paperback
• Number of pages: 192