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Gene Regulation by Numbers: Steady-State and Equilibrium Binding Applied to Gene Regulation Systems - Softcover
Synopsis
This thesis is composed of three parts that are presented in a hierarchical order reflecting increasing organization level of the studied system. Gene regulation was studied at the single gene level first, extended to interacting transcriptional units and finally to its role within small regulatory networks. Our approach consists of an iterative experimental-based mathematical modeling based on promoter libraries with synthetic binding site sequences of variable affinities for selected transcriptional activators. We used such libraries to perform in vivo experiments using the yeast Saccharomyces cerevisiae in order to improve our theoretical models. The main goal of the work is the determination of gene system’s intrinsic properties like cooperativity coefficients and binding affinities of transcription factors to DNA regulatory sequences.
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About the Author
Antoine Buetti-Dinh, Swiss, born 21st October 1984, in Paris, France.PhD in Physical Systems Biology, Institute of Molecular Life Sciences, University of Zurich.Master of Science in Biochemistry, Biology Track, Department of Biochemistry, University of Zurich.Bachelor of Science in Biochemistry, Biology Track.Department of Biochemistry.
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Gene Regulation by Numbers
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Südwestdeutscher Verlag Für Hochschulschriften AG Co. KG Jul 2015, 2015
ISBN 10: 3838132882
ISBN 13: 9783838132884
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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This thesis is composed of three parts that are presented in a hierarchical order reflecting increasing organization level of the studied system. Gene regulation was studied at the single gene level first, extended to interacting transcriptional units and finally to its role within small regulatory networks. Our approach consists of an iterative experimental-based mathematical modeling based on promoter libraries with synthetic binding site sequences of variable affinities for selected transcriptional activators. We used such libraries to perform in vivo experiments using the yeast Saccharomyces cerevisiae in order to improve our theoretical models. The main goal of the work is the determination of gene system's intrinsic properties like cooperativity coefficients and binding affinities of transcription factors to DNA regulatory sequences. 228 pp. Englisch. Seller Inventory # 9783838132884
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Gene Regulation by Numbers
Published by
Südwestdeutscher Verlag für Hochschulschriften, 2012
ISBN 10: 3838132882
ISBN 13: 9783838132884
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Softcover
Seller: moluna, Greven, Germany
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Antoine Buetti-DinhAntoine Buetti-Dinh, Swiss, born 21st October 1984, in Paris, France.PhD in Physical Systems Biology, Institute of Molecular Life Sciences, University of Zurich.Master of Science in Biochemistry, Biology Track, Dep. Seller Inventory # 5407570
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Gene Regulation by Numbers : Steady-State and Equilibrium Binding Applied to Gene Regulation Systems
Published by
Südwestdeutscher Verlag Für Hochschulschriften AG Co. KG, 2012
ISBN 10: 3838132882
ISBN 13: 9783838132884
New
Taschenbuch
Seller: AHA-BUCH GmbH, Einbeck, Germany
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - This thesis is composed of three parts that are presented in a hierarchical order reflecting increasing organization level of the studied system. Gene regulation was studied at the single gene level first, extended to interacting transcriptional units and finally to its role within small regulatory networks. Our approach consists of an iterative experimental-based mathematical modeling based on promoter libraries with synthetic binding site sequences of variable affinities for selected transcriptional activators. We used such libraries to perform in vivo experiments using the yeast Saccharomyces cerevisiae in order to improve our theoretical models. The main goal of the work is the determination of gene system's intrinsic properties like cooperativity coefficients and binding affinities of transcription factors to DNA regulatory sequences. Seller Inventory # 9783838132884
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Gene Regulation by Numbers | Steady-State and Equilibrium Binding Applied to Gene Regulation Systems
Published by
Südwestdeutscher Verlag für Hochschulschriften AG Co. KG, 2015
ISBN 10: 3838132882
ISBN 13: 9783838132884
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Taschenbuch. Condition: Neu. Gene Regulation by Numbers | Steady-State and Equilibrium Binding Applied to Gene Regulation Systems | Buetti-Dinh Antoine | Taschenbuch | Paperback | 228 S. | Englisch | 2015 | Südwestdeutscher Verlag für Hochschulschriften AG Co. KG | EAN 9783838132884 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu. Seller Inventory # 106502517
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Gene Regulation by Numbers
Published by
Südwestdeutscher Verlag Für Hochschulschriften AG Co. KG Jul 2015, 2015
ISBN 10: 3838132882
ISBN 13: 9783838132884
New
Taschenbuch
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germany
Seller rating 5 out of 5 stars
Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This thesis is composed of three parts that are presented in a hierarchical order reflecting increasing organization level of the studied system. Gene regulation was studied at the single gene level first, extended to interacting transcriptional units and finally to its role within small regulatory networks. Our approach consists of an iterative experimental-based mathematical modeling based on promoter libraries with synthetic binding site sequences of variable affinities for selected transcriptional activators. We used such libraries to perform in vivo experiments using the yeast Saccharomyces cerevisiae in order to improve our theoretical models. The main goal of the work is the determination of gene system's intrinsic properties like cooperativity coefficients and binding affinities of transcription factors to DNA regulatory sequences.Books on Demand GmbH, Überseering 33, 22297 Hamburg 228 pp. Englisch. Seller Inventory # 9783838132884