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MicroRNA Regulation of Dendritic Cells: Experimental studies on the role of microRNAs in dendritic cell development and function - Softcover
Synopsis
Dendritic cells (DCs) play a key role in the initiation of adaptive immune responses and the maintenance of immunological self-tolerance. Due to their therapeutic potential, understanding the mechanisms that guide DC differentiation and effector functions is important. The recent identification of posttranscriptional control of gene expression by microRNAs has added a novel layer of gene regulation that may be important in DC biology. The experimental work presented and discussed here indicates a role for microRNAs in DC regulation that is not covered by transcription factors. An essential role for microRNAs in DC lineage fate decisions, as well as in homeostasis, maturation and function of Langerhans cells (the epidermal DCs) is demonstrated. Thus, microRNAs regulate various aspects of DC biology and thereby contribute to the control of adaptive immune responses.
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About the Author
Frauke Marie Schnorfeil, Dr. rer. nat., studied Biology focusing on Human Genetics and Immunology. In 2011, she received her doctoral degree from the LMU Munich, Germany, for her research on dendritic cells.
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MicroRNA Regulation of Dendritic Cells
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Südwestdeutscher Verlag Für Hochschulschriften Mrz 2012, 2012
ISBN 10: 3838131894
ISBN 13: 9783838131894
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Dendritic cells (DCs) play a key role in the initiation of adaptive immune responses and the maintenance of immunological self-tolerance. Due to their therapeutic potential, understanding the mechanisms that guide DC differentiation and effector functions is important. The recent identification of posttranscriptional control of gene expression by microRNAs has added a novel layer of gene regulation that may be important in DC biology. The experimental work presented and discussed here indicates a role for microRNAs in DC regulation that is not covered by transcription factors. An essential role for microRNAs in DC lineage fate decisions, as well as in homeostasis, maturation and function of Langerhans cells (the epidermal DCs) is demonstrated. Thus, microRNAs regulate various aspects of DC biology and thereby contribute to the control of adaptive immune responses. 88 pp. Englisch. Seller Inventory # 9783838131894
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MicroRNA Regulation of Dendritic Cells : Experimental studies on the role of microRNAs in dendritic cell development and function
Published by
Südwestdeutscher Verlag Für Hochschulschriften, 2012
ISBN 10: 3838131894
ISBN 13: 9783838131894
New
Taschenbuch
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Dendritic cells (DCs) play a key role in the initiation of adaptive immune responses and the maintenance of immunological self-tolerance. Due to their therapeutic potential, understanding the mechanisms that guide DC differentiation and effector functions is important. The recent identification of posttranscriptional control of gene expression by microRNAs has added a novel layer of gene regulation that may be important in DC biology. The experimental work presented and discussed here indicates a role for microRNAs in DC regulation that is not covered by transcription factors. An essential role for microRNAs in DC lineage fate decisions, as well as in homeostasis, maturation and function of Langerhans cells (the epidermal DCs) is demonstrated. Thus, microRNAs regulate various aspects of DC biology and thereby contribute to the control of adaptive immune responses. Seller Inventory # 9783838131894
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MicroRNA Regulation of Dendritic Cells
Published by
Südwestdeutscher Verlag für Hochschulschriften, 2012
ISBN 10: 3838131894
ISBN 13: 9783838131894
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Schnorfeil Frauke MarieFrauke Marie Schnorfeil, Dr. rer. nat., studied Biology focusing on Human Genetics and Immunology. In 2011, she received her doctoral degree from the LMU Munich, Germany, for her research on dendritic cells. Seller Inventory # 5407473
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MicroRNA Regulation of Dendritic Cells
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Südwestdeutscher Verlag Für Hochschulschriften Mär 2012, 2012
ISBN 10: 3838131894
ISBN 13: 9783838131894
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Dendritic cells (DCs) play a key role in the initiation of adaptive immune responses and the maintenance of immunological self-tolerance. Due to their therapeutic potential, understanding the mechanisms that guide DC differentiation and effector functions is important. The recent identification of posttranscriptional control of gene expression by microRNAs has added a novel layer of gene regulation that may be important in DC biology. The experimental work presented and discussed here indicates a role for microRNAs in DC regulation that is not covered by transcription factors. An essential role for microRNAs in DC lineage fate decisions, as well as in homeostasis, maturation and function of Langerhans cells (the epidermal DCs) is demonstrated. Thus, microRNAs regulate various aspects of DC biology and thereby contribute to the control of adaptive immune responses.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 88 pp. Englisch. Seller Inventory # 9783838131894
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MicroRNA Regulation of Dendritic Cells | Experimental studies on the role of microRNAs in dendritic cell development and function
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Südwestdeutscher Verlag für Hochschulschriften, 2015
ISBN 10: 3838131894
ISBN 13: 9783838131894
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Taschenbuch. Condition: Neu. MicroRNA Regulation of Dendritic Cells | Experimental studies on the role of microRNAs in dendritic cell development and function | Frauke Marie Schnorfeil | Taschenbuch | 88 S. | Englisch | 2015 | Südwestdeutscher Verlag für Hochschulschriften | EAN 9783838131894 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Seller Inventory # 106590597