Items related to Cell Volume Regulation: 123 (Contributions to Nephrology,...

Cell Volume Regulation: 123 (Contributions to Nephrology, 123) - Softcover

 
9783805567374: Cell Volume Regulation: 123 (Contributions to Nephrology, 123)

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Synopsis

This volume presents a unique compilation of reviews on cell volume regulation in health and disease, with contributions from leading experts in the field. The topics covered include mechanisms and signaling of cell volume regulation and the effect of cell volume on cell function, with special emphasis on ion channels and transporters, kinases and gene expression. Several chapters elaborate on how cell volume regulatory mechanisms participate in the regulation of epithelial transport, urinary concentration, metabolism, migration, cell proliferation and apoptosis. Last but not least, this publication is an excellent guide to the role of cell volume in the pathophysiology of hypercatabolism, diabetes mellitus, brain edema, hemoglobinopathies, tumor growth and metastasis, to name just a few. Providing deeper insights into an exciting area of research which is also of clinical relevance, this publication is a valuable addition to the library of those interested in cell volume regulation.

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Synopsis

It is becoming clear that cell volume regulatory mechanisms are critically involved in the regulation of a wide variety of physiological functions including epithelial transport, neuromuscular excitability, hormone release, metabolism, immune response, migration, cell proliferation and cell death. Moreover, cell volume regulatory mechanisms participate in the pathophysiology of diverse diseases, such as diabeetes mellitus, inflammation, uremia, hepatic insufficiency and hypercatabolic states. This collection of brief reviews from scientists in the field is intended to allow deeper insight into mechanisms and significance of cell volume regulatory mechanisms and is hoped to foster further experimental effort in this clinically relevant area of research.

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