These are the proceedings of the 2nd international workshop on model-oriented data-analysis organized by the International Institute of Applied System Analysis (IIASA) and the Bulgarian Academy of Sciences. The majority of participants is closely related to the development of statistical methods of experimental design. The corresponding approaches are fundamentally based on the idea that a system (object and experiment) has to be described (approximated) by some mathematical model to make any experimental design reasonable. This fact has mainly initaited the choice of the workshops title. The reports cover the following areas: optimal experimental design, data analysis (mainly regression analysis), quality engineering and other applications.
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