Items related to Gene Therapy: 27 (Ernst Schering Foundation Symposium...
Synopsis
This book is a collection of preclinical and clinical reports on the application of gene therapy to human disease. The two methods available for delivering therapeutic genes to diseased cells, viral and non-viral vector systems, are detailed and characterized. Several reports describe both approaches currently used in gene therapy: the introduction of a wild-type gene to restore normal gene function in diseased cells, and the use of antisense molecules to hinder abnormal gene expression. Clinical studies detail several different strategies for the treatment of cancer and cardiovascular diseases, using genetic material as therapeutic agents. The regulatory issues governing the use of gene therapy in Europe and the United States are also presented. This book highlights the range of applications and demonstrates the rapid progress being made in the field of gene therapy.
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From the Back Cover
This book is a collection of preclinical and clinical reports on the application of gene therapy to human disease. The two methods available for delivering therapeutic genes to diseased cells, viral and non-viral vector systems, are detailed and characterized. Several reports describe both approaches currently used in gene therapy: the introduction of a wild-type gene to restore normal gene function in diseased cells, and the use of antisense molecules to hinder abnormal gene expression. Clinical studies detail several different strategies for the treatment of cancer and cardiovascular diseases, using genetic material as therapeutic agents. The regulatory issues governing the use of gene therapy in Europe and the United States are also presented. This book highlights the range of applications and demonstrates the rapid progress being made in the field of gene therapy.
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Gene Therapy (eng)
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Gene Therapy
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Gene Therapy (Ernst Schering Foundation Symposium Proceedings)
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Gene Therapy (Ernst Schering Foundation Symposium Proceedings, 27)
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Gene Therapy
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Springer Berlin Heidelberg Okt 2013, 2013
ISBN 10: 3662035790
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is a collection of preclinical and clinical reports on the appli cation of gene therapy to human disease. The focus of these studies is on cancer and cardiovascular disease. There are two fundamental technologies for delivering therapeutic genes to diseased ceHs: either viral vectors, as discussed by Dr. Bal main, or non-viral vector systems, as discussed by Dr. Felgner. The strengths and limitations of each of these delivery systems are charac terized. The use of a therapeutic gene to treat a disease has taken two general approaches. The first is to introduce anormal (i. e. , wild type) gene into the patient that will restore normal gene function. Dr. Weiss man has characterized the tumor suppressor gene (pS3), and has shown that it can restore normal ceH function in cancer cells. The second ap proach is to treat the disease with antisense molecules. Abnormal gene expression can be down-regulated and selectively inhibited by anti sense molecules, which can reverse the pathologie process in cancer cells. Dr. Gewirtz has demonstrated this with anti sense genes on leuke mia, while Dr. Scanlon has applied this principle using ribozymes in human carcinomas. During this symposium, Dr. Engler described clinical studies of gene therapy using growth factors to stimulate new blood vessels in patients with cardiovascular disease. Several gene therapy strategies were used for cancer: overcoming drug resistance by Dr. Bertino, a pro-drug strategy with ganciclovir by Dr. 256 pp. Englisch. Seller Inventory # 9783662035795
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Gene Therapy
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Gene Therapy (Ernst Schering Foundation Symposium Proceedings)
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Gene Therapy
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Gene Therapy
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Condition: New. Print on Demand pp. 256 25:B&W 5.83 x 8.27 in or 210 x 148 mm (A5) Perfect Bound on White w/Gloss Lam. Seller Inventory # 131315505
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Gene Therapy
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. This book is a collection of preclinical and clinical reports on the application of gene therapy to human disease. The two methods available for delivering therapeutic genes to diseased cells, viral and non-viral vector systems, are detailed and characteriz. Seller Inventory # 5221491
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