Synopsis
Diabetic ketoacidosis ( DKA ) is the most common hyper-glycemic emergency in patients with diabetes, and it was caused by too much ketones. Among the total ketone body, D-3-hydroxybutyric acid ( D-3-HB ) is the major, nearly 78%. So the detection of serum D-3-HB has been a routine marker for diagnosis of diabetic ketoacidosis. Fluorescent detection is the most efficient method, operational simplicity, low cost, real time monitoring and high sensitivity. Here, Two novel probe, 4-(2-hydroxybenzylicene)thiosemicarbazide ( 1 ) and 4-(1H- imidazo[4,5-f][1,10]- phenanthrolin-2-yl)phenol ( 2 ), were synthesized and shown a peculiar OFF-ON fluorescent response to D-3-HB in aqueous. The probe 1 & 2 have exhibited a selective and sensitive response to the D-3-HB over other common metal ions, anions and amino acids. Moreover the mechanism was confirmed by 1H-NMR and ESI-MS. Furthermore, this probe 1 successfully applied to bioimaging, demonstrating its value of practical applications in biological systems.
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About the Author
Qingming Wang was born in Jiangsu,China, in 1984. He received his PhD in 2012 from Shanxi University. Subsequently he became an associate professor in Yancheng Teachers' University, China. His recent research focuses on the synthesis of optical probes based on fluorescein, coumarin, chromene, supramolecular chemistry and chiral molecules.
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Highly selective OFF-ON fluorescent sensor for D-3-HB in aqueous
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LAP Lambert Academic Publishing Sep 2016, 2016
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ISBN 13: 9783659953675
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Diabetic ketoacidosis ( DKA ) is the most common hyper-glycemic emergency in patients with diabetes, and it was caused by too much ketones. Among the total ketone body, D-3-hydroxybutyric acid ( D-3-HB ) is the major, nearly 78%. So the detection of serum D-3-HB has been a routine marker for diagnosis of diabetic ketoacidosis. Fluorescent detection is the most efficient method, operational simplicity, low cost, real time monitoring and high sensitivity. Here, Two novel probe, 4-(2-hydroxybenzylicene)thiosemicarbazide ( 1 ) and 4-(1H- imidazo[4,5-f][1,10]- phenanthrolin-2-yl)phenol ( 2 ), were synthesized and shown a peculiar OFF-ON fluorescent response to D-3-HB in aqueous. The probe 1 & 2 have exhibited a selective and sensitive response to the D-3-HB over other common metal ions, anions and amino acids. Moreover the mechanism was confirmed by 1H-NMR and ESI-MS. Furthermore, this probe 1 successfully applied to bioimaging, demonstrating its value of practical applications in biological systems. 56 pp. Englisch. Seller Inventory # 9783659953675
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Highly selective OFF-ON fluorescent sensor for D-3-HB in aqueous
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Highly selective OFF-ON fluorescent sensor for D-3-HB in aqueous
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Wang QingmingQingming Wang was born in Jiangsu,China, in 1984. He received his PhD in 2012 from Shanxi University. Subsequently he became an associate professor in Yancheng Teachers University, China. His recent research focuses on . Seller Inventory # 158125627
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Highly selective OFF-ON fluorescent sensor for D-3-HB in aqueous
Published by
LAP Lambert Academic Publishing Sep 2016, 2016
ISBN 10: 3659953679
ISBN 13: 9783659953675
New
Taschenbuch
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Taschenbuch. Condition: Neu. Neuware -Diabetic ketoacidosis ( DKA ) is the most common hyper-glycemic emergency in patients with diabetes, and it was caused by too much ketones. Among the total ketone body, D-3-hydroxybutyric acid ( D-3-HB ) is the major, nearly 78%. So the detection of serum D-3-HB has been a routine marker for diagnosis of diabetic ketoacidosis. Fluorescent detection is the most efficient method, operational simplicity, low cost, real time monitoring and high sensitivity. Here, Two novel probe, 4-(2-hydroxybenzylicene)thiosemicarbazide ( 1 ) and 4-(1H- imidazo[4,5-f][1,10]- phenanthrolin-2-yl)phenol ( 2 ), were synthesized and shown a peculiar OFF-ON fluorescent response to D-3-HB in aqueous. The probe 1 & 2 have exhibited a selective and sensitive response to the D-3-HB over other common metal ions, anions and amino acids. Moreover the mechanism was confirmed by 1H-NMR and ESI-MS. Furthermore, this probe 1 successfully applied to bioimaging, demonstrating its value of practical applications in biological systems.Books on Demand GmbH, Überseering 33, 22297 Hamburg 56 pp. Englisch. Seller Inventory # 9783659953675
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Highly selective OFF-ON fluorescent sensor for D-3-HB in aqueous
Published by
LAP Lambert Academic Publishing, 2016
ISBN 10: 3659953679
ISBN 13: 9783659953675
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Taschenbuch
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Diabetic ketoacidosis ( DKA ) is the most common hyper-glycemic emergency in patients with diabetes, and it was caused by too much ketones. Among the total ketone body, D-3-hydroxybutyric acid ( D-3-HB ) is the major, nearly 78%. So the detection of serum D-3-HB has been a routine marker for diagnosis of diabetic ketoacidosis. Fluorescent detection is the most efficient method, operational simplicity, low cost, real time monitoring and high sensitivity. Here, Two novel probe, 4-(2-hydroxybenzylicene)thiosemicarbazide ( 1 ) and 4-(1H- imidazo[4,5-f][1,10]- phenanthrolin-2-yl)phenol ( 2 ), were synthesized and shown a peculiar OFF-ON fluorescent response to D-3-HB in aqueous. The probe 1 & 2 have exhibited a selective and sensitive response to the D-3-HB over other common metal ions, anions and amino acids. Moreover the mechanism was confirmed by 1H-NMR and ESI-MS. Furthermore, this probe 1 successfully applied to bioimaging, demonstrating its value of practical applications in biological systems. Seller Inventory # 9783659953675
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Highly selective OFF-ON fluorescent sensor for D-3-HB in aqueous
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ISBN 13: 9783659953675
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Taschenbuch. Condition: Neu. Highly selective OFF-ON fluorescent sensor for D-3-HB in aqueous | Qingming Wang | Taschenbuch | 56 S. | Englisch | 2016 | LAP Lambert Academic Publishing | EAN 9783659953675 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu. Seller Inventory # 103164268