Synopsis
Objective of the present study is to prepare edaravone nanoparticle by using 3 level factorial deign using design expect 9 software. The software produced 17 formulations with varying concentration of EC, PVA and Tween-80 with a fixed dose of edaravone (5 mg). The drug and polymer compatibility study was done by FTIR spectroscopy. All the 17 formulations morphology was spherical in shape and the zeta potential in the rage of -12.7 mV to -28.5 mV. The particle size and entrapment efficiency was the main independent variable in formula optimization. The in-vitro dissolution of all the formulations were followed initial burst release followed by sustained release more than 12 hours. Based on the factorial design studies, we optimized formulation of edaravone nanoparticle.
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About the Author
Dr.Varatharajan Rajavel has been completed M.Pharm in Industrial Pharmacy, Annamalai University, India and PhD in Pharmacology, University of Malaya, Kuala Lumpur, Malaysia. Presently working as a Associate Professor in Faculty of Pharmacy, Asian Institute of Medicine and Technology University (AIMST), Kedah, Malaysia.
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Edaravone Nanoparticles
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LAP LAMBERT Academic Publishing Sep 2017, 2017
ISBN 10: 3659851833
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Taschenbuch. Condition: Neu. Neuware -Objective of the present study is to prepare edaravone nanoparticle by using 3 level factorial deign using design expect 9 software. The software produced 17 formulations with varying concentration of EC, PVA and Tween-80 with a fixed dose of edaravone (5 mg). The drug and polymer compatibility study was done by FTIR spectroscopy. All the 17 formulations morphology was spherical in shape and the zeta potential in the rage of -12.7 mV to -28.5 mV. The particle size and entrapment efficiency was the main independent variable in formula optimization. The in-vitro dissolution of all the formulations were followed initial burst release followed by sustained release more than 12 hours. Based on the factorial design studies, we optimized formulation of edaravone nanoparticle. 84 pp. Englisch. Seller Inventory # 9783659851834
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Edaravone Nanoparticles: Surface Response Methodology
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Edaravone Nanoparticles
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Rajavel VaratharajanDr.Varatharajan Rajavel has been completed M.Pharm in Industrial Pharmacy, Annamalai University, India and PhD in Pharmacology, University of Malaya, Kuala Lumpur, Malaysia. Presently working as a Associate Profes. Seller Inventory # 173617036
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Edaravone Nanoparticles
Published by
LAP LAMBERT Academic Publishing Sep 2017, 2017
ISBN 10: 3659851833
ISBN 13: 9783659851834
New
Taschenbuch
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Objective of the present study is to prepare edaravone nanoparticle by using 3 level factorial deign using design expect 9 software. The software produced 17 formulations with varying concentration of EC, PVA and Tween-80 with a fixed dose of edaravone (5 mg). The drug and polymer compatibility study was done by FTIR spectroscopy. All the 17 formulations morphology was spherical in shape and the zeta potential in the rage of -12.7 mV to -28.5 mV. The particle size and entrapment efficiency was the main independent variable in formula optimization. The in-vitro dissolution of all the formulations were followed initial burst release followed by sustained release more than 12 hours. Based on the factorial design studies, we optimized formulation of edaravone nanoparticle.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 84 pp. Englisch. Seller Inventory # 9783659851834
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Edaravone Nanoparticles : Surface Response Methodology
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ISBN 10: 3659851833
ISBN 13: 9783659851834
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Objective of the present study is to prepare edaravone nanoparticle by using 3 level factorial deign using design expect 9 software. The software produced 17 formulations with varying concentration of EC, PVA and Tween-80 with a fixed dose of edaravone (5 mg). The drug and polymer compatibility study was done by FTIR spectroscopy. All the 17 formulations morphology was spherical in shape and the zeta potential in the rage of -12.7 mV to -28.5 mV. The particle size and entrapment efficiency was the main independent variable in formula optimization. The in-vitro dissolution of all the formulations were followed initial burst release followed by sustained release more than 12 hours. Based on the factorial design studies, we optimized formulation of edaravone nanoparticle. Seller Inventory # 9783659851834
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Edaravone Nanoparticles | Surface Response Methodology
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ISBN 13: 9783659851834
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Taschenbuch. Condition: Neu. Edaravone Nanoparticles | Surface Response Methodology | Varatharajan Rajavel (u. a.) | Taschenbuch | Englisch | 2017 | LAP LAMBERT Academic Publishing | EAN 9783659851834 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Seller Inventory # 113180318