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Synthesis and Glycosidase Inhibitory Activity of Azasugars: Novel synthesis of piperidine- and pyrrolidine-homoazasugars, bicyclic diazasugars and isofagomines as enzyme inhibitors - Softcover
Synopsis
There is growing interest amongst scientific community in a heterogeneous group of hydrophilic plant alkaloids like polyhydroxylated monocyclic piperidine, pyrrolidine and bicyclic indolizidine, pyrrolizidine, quinolizidine and nortropane owing to their potential biological activities. These alkaloids have been given various generic names e.g. azasugars, iminosugars, polyhydroxy alkaloids, aminosugars etc. So, azasugars are polyhydroxylated alkaloids in which the endocyclic oxygen atom of the sugar ring is replaced with the basic nitrogen. Mere this atomic substitution confers these compounds with the ability to mimic sugars and inhibit various carbohydrate processing enzymes; most significantly the glycosidases (glycoside hydrolases) which are intimately involved in a huge array of biological functions. The present book described the natural occurrence of piperidine homoazasugars, pyrrolidine homoazasugars, bicyclic diazasugars and 1-azasugars. The synthetic aspects of these azasugars using a number of methodologies including chemo-enzymatic methods have discussed. The structural basis for the specificity of glycosidase inhibition and biological application is also described.
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About the Author
Prof. Matin received his Ph.D. from the University of Pune, India and M.Sc. & B.Sc. (Honours) from the University of Chittagong, Bangladesh. He was the post-doctoral Fellow at Institute of Biological Sciences, Academia Sinica, Taiwan. He has a good teaching and research experience in the field of Organic, Bioorganic and Natural Product Chemistry.
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Synthesis and Glycosidase Inhibitory Activity of Azasugars
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LAP LAMBERT Academic Publishing Jul 2016, 2016
ISBN 10: 3659850888
ISBN 13: 9783659850882
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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -There is growing interest amongst scientific community in a heterogeneous group of hydrophilic plant alkaloids like polyhydroxylated monocyclic piperidine, pyrrolidine and bicyclic indolizidine, pyrrolizidine, quinolizidine and nortropane owing to their potential biological activities. These alkaloids have been given various generic names e.g. azasugars, iminosugars, polyhydroxy alkaloids, aminosugars etc. So, azasugars are polyhydroxylated alkaloids in which the endocyclic oxygen atom of the sugar ring is replaced with the basic nitrogen. Mere this atomic substitution confers these compounds with the ability to mimic sugars and inhibit various carbohydrate processing enzymes; most significantly the glycosidases (glycoside hydrolases) which are intimately involved in a huge array of biological functions. The present book described the natural occurrence of piperidine homoazasugars, pyrrolidine homoazasugars, bicyclic diazasugars and 1-azasugars. The synthetic aspects of these azasugars using a number of methodologies including chemo-enzymatic methods have discussed. The structural basis for the specificity of glycosidase inhibition and biological application is also described. 284 pp. Englisch. Seller Inventory # 9783659850882
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Synthesis and Glycosidase Inhibitory Activity of Azasugars
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ISBN 10: 3659850888
ISBN 13: 9783659850882
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Matin Mohammed MahbubulProf. Matin received his Ph.D. from the University of Pune, India and M.Sc. & B.Sc. (Honours) from the University of Chittagong, Bangladesh. He was the post-doctoral Fellow at Institute of Biological Sciences, . Seller Inventory # 158606007
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Synthesis and Glycosidase Inhibitory Activity of Azasugars: Novel synthesis of piperidine- and pyrrolidine-homoazasugars, bicyclic diazasugars and isofagomines as enzyme inhibitors
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Synthesis and Glycosidase Inhibitory Activity of Azasugars: Novel synthesis of piperidine- and pyrrolidine-homoazasugars, bicyclic diazasugars and isofagomines as enzyme inhibitors
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Synthesis and Glycosidase Inhibitory Activity of Azasugars: Novel synthesis of piperidine- and pyrrolidine-homoazasugars, bicyclic diazasugars and isofagomines as enzyme inhibitors
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Synthesis and Glycosidase Inhibitory Activity of Azasugars
Published by
LAP LAMBERT Academic Publishing Jul 2016, 2016
ISBN 10: 3659850888
ISBN 13: 9783659850882
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Taschenbuch
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -There is growing interest amongst scientific community in a heterogeneous group of hydrophilic plant alkaloids like polyhydroxylated monocyclic piperidine, pyrrolidine and bicyclic indolizidine, pyrrolizidine, quinolizidine and nortropane owing to their potential biological activities. These alkaloids have been given various generic names e.g. azasugars, iminosugars, polyhydroxy alkaloids, aminosugars etc. So, azasugars are polyhydroxylated alkaloids in which the endocyclic oxygen atom of the sugar ring is replaced with the basic nitrogen. Mere this atomic substitution confers these compounds with the ability to mimic sugars and inhibit various carbohydrate processing enzymes; most significantly the glycosidases (glycoside hydrolases) which are intimately involved in a huge array of biological functions. The present book described the natural occurrence of piperidine homoazasugars, pyrrolidine homoazasugars, bicyclic diazasugars and 1-azasugars. The synthetic aspects of these azasugars using a number of methodologies including chemo-enzymatic methods have discussed. The structural basis for the specificity of glycosidase inhibition and biological application is also described.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 284 pp. Englisch. Seller Inventory # 9783659850882
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Synthesis and Glycosidase Inhibitory Activity of Azasugars : Novel synthesis of piperidine- and pyrrolidine-homoazasugars, bicyclic diazasugars and isofagomines as enzyme inhibitors
Published by
LAP LAMBERT Academic Publishing, 2016
ISBN 10: 3659850888
ISBN 13: 9783659850882
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - There is growing interest amongst scientific community in a heterogeneous group of hydrophilic plant alkaloids like polyhydroxylated monocyclic piperidine, pyrrolidine and bicyclic indolizidine, pyrrolizidine, quinolizidine and nortropane owing to their potential biological activities. These alkaloids have been given various generic names e.g. azasugars, iminosugars, polyhydroxy alkaloids, aminosugars etc. So, azasugars are polyhydroxylated alkaloids in which the endocyclic oxygen atom of the sugar ring is replaced with the basic nitrogen. Mere this atomic substitution confers these compounds with the ability to mimic sugars and inhibit various carbohydrate processing enzymes; most significantly the glycosidases (glycoside hydrolases) which are intimately involved in a huge array of biological functions. The present book described the natural occurrence of piperidine homoazasugars, pyrrolidine homoazasugars, bicyclic diazasugars and 1-azasugars. The synthetic aspects of these azasugars using a number of methodologies including chemo-enzymatic methods have discussed. The structural basis for the specificity of glycosidase inhibition and biological application is also described. Seller Inventory # 9783659850882
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Synthesis and Glycosidase Inhibitory Activity of Azasugars: Novel synthesis of piperidine- and pyrrolidine-homoazasugars, bicyclic diazasugars and isofagomines as enzyme inhibitors
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ISBN 13: 9783659850882
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Synthesis and Glycosidase Inhibitory Activity of Azasugars: Novel synthesis of piperidine- and pyrrolidine-homoazasugars, bicyclic diazasugars and isofagomines as enzyme inhibitors
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ISBN 13: 9783659850882
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