Exploring the Referentially-compressed Genomes: Advantages and Challenges - Softcover

Nassef, Mohammad; Badr, Amr; Farag, Ibrahim

Softcover

ISBN 10: 3659791121 ISBN 13: 9783659791123

Publisher: LAP LAMBERT Academic Publishing, 2015

Synopsis

Modern genome sequencing technologies produce enormous amount of data daily. Biologists in turn are keen to precisely explore this genomic data in order to discover effective patterns that have a real impact on the function and evolution of living creatures. Therefore, it becomes very critical to professionally store this data in order to efficiently explore it in a frequent manner. Reference-based Compression algorithms (RbCs) efficiently compress the sequenced genomes by mainly storing their differences with respect to a reference genome. Therefore, RbCs give amazing compression ratios compared to the traditional compression algorithms. However, in order to explore a compressed genome, it has to be totally decompressed, wasting both time and storage. By avoiding their complete decompression, the compressed genomes can be explored by performing partial decompressions at specific regions, gaining a significant reduction in runtime, memory, and storage consumption. Moreover, the complete decompression of a compressed genome can be performed more efficiently through successive partial decompressions.

About this title

About the Author

Dr. Mohammad Nassef is a lecturer at department of Computer Science, Faculty of Computers and Information, Cairo University, Egypt. He is interested in the research areas of Bioinformatics and Parallel Computing. This work is done in collaboration with Prof. Amr Badr and Prof. Ibrahim Farag, Faculty of Computers and Information, Cairo University.

Edition details

• Publisher: LAP LAMBERT Academic Publishing
• Publication date: 2015
• Language: English
• ISBN 10: 3659791121
• ISBN 13: 9783659791123
• Binding: Paperback
• Number of pages: 108