Development of the central nervous system remains under strict control of the cell cycle. Spatial and temporal onset and completion of both neuro- and gliogenesis are regulated by several cell cycle proteins. Importantly, proteins comprising G1 phase regulatory network are involved in the control of stemness and/or lineage commitment balance in the pools of neural stem cells throughout the development. Deviation from this balance may lead to aberrant changes in cell division resulting in formation of brain tumour initiating cells (BTICs) which are at the source of human glioblastoma. This book provides a brief review of the cell cycle regulation at the embryonic and postnatal stages of neural development. Based on recent literature, a discussion on the role of G1 phase cyclins, cell cycle inhibitors and a novel cell cycle regulator, Spy1, in neural cell fate decisions, including mode of division and brain tumour formation, is provided in detail. The content of this book will aid in understanding how normal neural cells rely on cell cycle to control their growth and differentiation throughout life and how aberrant changes to certain cell cycle proteins contribute to gliomagenesis
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Research Associate at the Department of Biological Sciences at the University of Windsor, Canada, where she obtained her PhD in 2013. Her research involves cell cycle control mechanisms in human glioblastoma and during neurogenesis. Recently published a study in Cancer Cell on cell cycle regulation and mode of division in glioma initiating cells.
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Development of the central nervous system remains under strict control of the cell cycle. Spatial and temporal onset and completion of both neuro- and gliogenesis are regulated by several cell cycle proteins. Importantly, proteins comprising G1 phase regulatory network are involved in the control of stemness and/or lineage commitment balance in the pools of neural stem cells throughout the development. Deviation from this balance may lead to aberrant changes in cell division resulting in formation of brain tumour initiating cells (BTICs) which are at the source of human glioblastoma. This book provides a brief review of the cell cycle regulation at the embryonic and postnatal stages of neural development. Based on recent literature, a discussion on the role of G1 phase cyclins, cell cycle inhibitors and a novel cell cycle regulator, Spy1, in neural cell fate decisions, including mode of division and brain tumour formation, is provided in detail. The content of this book will aid in understanding how normal neural cells rely on cell cycle to control their growth and differentiation throughout life and how aberrant changes to certain cell cycle proteins contribute to gliomagenesis 88 pp. Englisch. Seller Inventory # 9783659547782
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Lubanska DorotaResearch Associate at the Department of Biological Sciences at the University of Windsor, Canada, where she obtained her PhD in 2013. Her research involves cell cycle control mechanisms in human glioblastoma and during. Seller Inventory # 5163976
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Development of the central nervous system remains under strict control of the cell cycle. Spatial and temporal onset and completion of both neuro- and gliogenesis are regulated by several cell cycle proteins. Importantly, proteins comprising G1 phase regulatory network are involved in the control of stemness and/or lineage commitment balance in the pools of neural stem cells throughout the development. Deviation from this balance may lead to aberrant changes in cell division resulting in formation of brain tumour initiating cells (BTICs) which are at the source of human glioblastoma. This book provides a brief review of the cell cycle regulation at the embryonic and postnatal stages of neural development. Based on recent literature, a discussion on the role of G1 phase cyclins, cell cycle inhibitors and a novel cell cycle regulator, Spy1, in neural cell fate decisions, including mode of division and brain tumour formation, is provided in detail. The content of this book will aid in understanding how normal neural cells rely on cell cycle to control their growth and differentiation throughout life and how aberrant changes to certain cell cycle proteins contribute to gliomagenesisVDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 88 pp. Englisch. Seller Inventory # 9783659547782
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Development of the central nervous system remains under strict control of the cell cycle. Spatial and temporal onset and completion of both neuro- and gliogenesis are regulated by several cell cycle proteins. Importantly, proteins comprising G1 phase regulatory network are involved in the control of stemness and/or lineage commitment balance in the pools of neural stem cells throughout the development. Deviation from this balance may lead to aberrant changes in cell division resulting in formation of brain tumour initiating cells (BTICs) which are at the source of human glioblastoma. This book provides a brief review of the cell cycle regulation at the embryonic and postnatal stages of neural development. Based on recent literature, a discussion on the role of G1 phase cyclins, cell cycle inhibitors and a novel cell cycle regulator, Spy1, in neural cell fate decisions, including mode of division and brain tumour formation, is provided in detail. The content of this book will aid in understanding how normal neural cells rely on cell cycle to control their growth and differentiation throughout life and how aberrant changes to certain cell cycle proteins contribute to gliomagenesis. Seller Inventory # 9783659547782
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Taschenbuch. Condition: Neu. Cell Cycle Control, Cell Fate Decisions and the Central Nervous System | Implications in Brain Tumour Formation | Dorota Lubanska (u. a.) | Taschenbuch | 88 S. | Englisch | 2014 | LAP LAMBERT Academic Publishing | EAN 9783659547782 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Seller Inventory # 105227459
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