Synopsis
Sustained release formulations often face the challenge of finding the right combination of formulation variables that will produce a product with optimum properties. Optimization becomes even more important when the formulation is a sustained-release dosage form, since many often-interdependent factors can affect the release rate. In this study, we have investigated the effect of formulation variables on several responses. Subsequently, response surface methodology was applied to optimize the formulation after constructing a desirability function that simultaneously combines all the four responses. Formulations of loxoprofen-loaded sustained release microspheres were prepared by solvent evaporation technique and optimized using response surface methodology by fitting a second-order model to the response data. This book provides a detailed discussion on chemometric procedure for the optimization of formulation variables, development of regression models and global optimization of response variables to design quality formulation. This work could form a reference material to those aspiring to pursue research in the design, development and optimization of microspheres.
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About the Author
Dr.P.Venkatesan is working as Assistant professor, Department of Pharmacy, Annamalai University,India. His research interest is in the design, development and optimization of NDDS. He has a number of research publications in peer reviewed journals of repute to his credit. Dr. Venkatesan is the Deputy Coordinator of the UGC SAP DRS Phase-l Project.
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Formulation of loxoprofen loaded-microspheres
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Sustained release formulations often face the challenge of finding the right combination of formulation variables that will produce a product with optimum properties. Optimization becomes even more important when the formulation is a sustained-release dosage form, since many often-interdependent factors can affect the release rate. In this study, we have investigated the effect of formulation variables on several responses. Subsequently, response surface methodology was applied to optimize the formulation after constructing a desirability function that simultaneously combines all the four responses. Formulations of loxoprofen-loaded sustained release microspheres were prepared by solvent evaporation technique and optimized using response surface methodology by fitting a second-order model to the response data. This book provides a detailed discussion on chemometric procedure for the optimization of formulation variables, development of regression models and global optimization of response variables to design quality formulation. This work could form a reference material to those aspiring to pursue research in the design, development and optimization of microspheres. 220 pp. Englisch. Seller Inventory # 9783659436376
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Formulation of loxoprofen loaded-microspheres
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Venkatesan PalanivelDr.P.Venkatesan is working as Assistant professor, Department of Pharmacy, Annamalai University,India. His research interest is in the design, development and optimization of NDDS. He has a number of research publ. Seller Inventory # 5156128
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Formulation of loxoprofen loaded-microspheres
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Sustained release formulations often face the challenge of finding the right combination of formulation variables that will produce a product with optimum properties. Optimization becomes even more important when the formulation is a sustained-release dosage form, since many often-interdependent factors can affect the release rate. In this study, we have investigated the effect of formulation variables on several responses. Subsequently, response surface methodology was applied to optimize the formulation after constructing a desirability function that simultaneously combines all the four responses. Formulations of loxoprofen-loaded sustained release microspheres were prepared by solvent evaporation technique and optimized using response surface methodology by fitting a second-order model to the response data. This book provides a detailed discussion on chemometric procedure for the optimization of formulation variables, development of regression models and global optimization of response variables to design quality formulation. This work could form a reference material to those aspiring to pursue research in the design, development and optimization of microspheres.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 220 pp. Englisch. Seller Inventory # 9783659436376
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Formulation of loxoprofen loaded-microspheres : Optimization using chemometric protocol
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Sustained release formulations often face the challenge of finding the right combination of formulation variables that will produce a product with optimum properties. Optimization becomes even more important when the formulation is a sustained-release dosage form, since many often-interdependent factors can affect the release rate. In this study, we have investigated the effect of formulation variables on several responses. Subsequently, response surface methodology was applied to optimize the formulation after constructing a desirability function that simultaneously combines all the four responses. Formulations of loxoprofen-loaded sustained release microspheres were prepared by solvent evaporation technique and optimized using response surface methodology by fitting a second-order model to the response data. This book provides a detailed discussion on chemometric procedure for the optimization of formulation variables, development of regression models and global optimization of response variables to design quality formulation. This work could form a reference material to those aspiring to pursue research in the design, development and optimization of microspheres. Seller Inventory # 9783659436376
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Formulation Of Loxoprofen Loaded-Microspheres: Optimization Using Chemometric Protocol
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