Formulation Development of Extended Released Rifaximin Micro-particles - Softcover

Bhise Kiran; Karanje Rohan

 
9783659418402: Formulation Development of Extended Released Rifaximin Micro-particles
Softcover
ISBN 10: 3659418404 ISBN 13: 9783659418402
Publisher: LAP Lambert Academic Publishing, 2015

Synopsis

This book addresses the formulation and process design aspects of extended release micro particles of BCS class IV drug Rifaximin through cyclodextrin complexation and extending the drug release by Eudragit L -100 enteric coating. The concept of surface response methodology was used in the selection of optimized batch that was further evaluated for various parameters. The data supports an improvement in aqueous solubility of BCS class IV drugs through cyclodextrin complexes. The release of such inclusion complexes can be retarded for 8 hrs by enteric coating.

"synopsis" may belong to another edition of this title.

Publisher
LAP Lambert Academic Publishing
Publication date
2015
Language
English
ISBN 10 
3659418404
ISBN 13 
9783659418402
Binding
Paperback
Number of pages
128