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Synopsis
To formulate and evaluate time dependent pulsatile drug delivery system of Montelukast sodium to deliver the drug with biological rhythm of asthma after predetermined lag time 5:30 hours. In preliminary study, The core tablet of Montelukast sodium was prepared by using direct compression method containing SSG, Croscarmellose sodium, Crospovidone, MCC and Starcap1500 to obtain fast disintegrating tablet for the selection of super disintegrating agent. PVAP, CAP and Ratio of Eudragit L 100: Eudragit S 100 was used as pH dependent polymer for coating the core tablets. Total 9 batches were formulated as per 32 full factorial design applied to check the effect of polymer ratio (Eudragit L 100: Eudragit S 100) and the effect of % weight gain on dependent variable lag time PRTs. These formulations were evaluated for physical parameters of tablet, drug -excipient compatibility study, lag time of rupture of PRTs and in-vitro drug release study. PDDS of Montelukast Sodium formulated using Croscarmellose sodium as super disintegrant and Eudragit L 100 and Eudragit S 100 as a coating polymers. Formulation M7 can provide site specific delivery with sigmoidal drug release.
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About the Author
My name is Kunal Modi.I completed my B.Pharm study from APMC college of Pharmaceutical Education and Research,Himatanagar.After that i completed my M.Pharm study from Shri B.M.Shah college of Pharmaceutical Education and Research,Modasa. I done my Project on Design and Development of Time Dependent Montelukast Sodium Tablet during my m.Pharm study
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Design and Development of Time Dependent Montelukast Sodium Tablet
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Design and Development of Time Dependent Montelukast Sodium Tablet
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Design and Development of Time Dependent Montelukast Sodium Tablet
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Design and Development of Time Dependent Montelukast Sodium Tablet
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Design and Development of Time Dependent Montelukast Sodium Tablet
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -To formulate and evaluate time dependent pulsatile drug delivery system of Montelukast sodium to deliver the drug with biological rhythm of asthma after predetermined lag time 5:30 hours. In preliminary study, The core tablet of Montelukast sodium was prepared by using direct compression method containing SSG, Croscarmellose sodium, Crospovidone, MCC and Starcap1500 to obtain fast disintegrating tablet for the selection of super disintegrating agent. PVAP, CAP and Ratio of Eudragit L 100: Eudragit S 100 was used as pH dependent polymer for coating the core tablets. Total 9 batches were formulated as per 32 full factorial design applied to check the effect of polymer ratio (Eudragit L 100: Eudragit S 100) and the effect of % weight gain on dependent variable lag time PRTs. These formulations were evaluated for physical parameters of tablet, drug -excipient compatibility study, lag time of rupture of PRTs and in-vitro drug release study. PDDS of Montelukast Sodium formulated using Croscarmellose sodium as super disintegrant and Eudragit L 100 and Eudragit S 100 as a coating polymers. Formulation M7 can provide site specific delivery with sigmoidal drug release. 96 pp. Englisch. Seller Inventory # 9783659408816
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Design and Development of Time Dependent Montelukast Sodium Tablet
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Design and Development of Time Dependent Montelukast Sodium Tablet
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ISBN 13: 9783659408816
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - To formulate and evaluate time dependent pulsatile drug delivery system of Montelukast sodium to deliver the drug with biological rhythm of asthma after predetermined lag time 5:30 hours. In preliminary study, The core tablet of Montelukast sodium was prepared by using direct compression method containing SSG, Croscarmellose sodium, Crospovidone, MCC and Starcap1500 to obtain fast disintegrating tablet for the selection of super disintegrating agent. PVAP, CAP and Ratio of Eudragit L 100: Eudragit S 100 was used as pH dependent polymer for coating the core tablets. Total 9 batches were formulated as per 32 full factorial design applied to check the effect of polymer ratio (Eudragit L 100: Eudragit S 100) and the effect of % weight gain on dependent variable lag time PRTs. These formulations were evaluated for physical parameters of tablet, drug -excipient compatibility study, lag time of rupture of PRTs and in-vitro drug release study. PDDS of Montelukast Sodium formulated using Croscarmellose sodium as super disintegrant and Eudragit L 100 and Eudragit S 100 as a coating polymers. Formulation M7 can provide site specific delivery with sigmoidal drug release. Seller Inventory # 9783659408816
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Design and Development of Time Dependent Montelukast Sodium Tablet
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Modi KunalMy name is Kunal Modi.I completed my B.Pharm study from APMC college of Pharmaceutical Education and Research,Himatanagar.After that i completed my M.Pharm study from Shri B.M.Shah college of Pharmaceutical Education and Re. Seller Inventory # 5154380
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Design and Development of Time Dependent Montelukast Sodium Tablet
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LAP LAMBERT Academic Publishing Jun 2013, 2013
ISBN 10: 3659408816
ISBN 13: 9783659408816
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -To formulate and evaluate time dependent pulsatile drug delivery system of Montelukast sodium to deliver the drug with biological rhythm of asthma after predetermined lag time 5:30 hours. In preliminary study, The core tablet of Montelukast sodium was prepared by using direct compression method containing SSG, Croscarmellose sodium, Crospovidone, MCC and Starcap1500 to obtain fast disintegrating tablet for the selection of super disintegrating agent. PVAP, CAP and Ratio of Eudragit L 100: Eudragit S 100 was used as pH dependent polymer for coating the core tablets. Total 9 batches were formulated as per 32 full factorial design applied to check the effect of polymer ratio (Eudragit L 100: Eudragit S 100) and the effect of % weight gain on dependent variable lag time PRTs. These formulations were evaluated for physical parameters of tablet, drug -excipient compatibility study, lag time of rupture of PRTs and in-vitro drug release study. PDDS of Montelukast Sodium formulated using Croscarmellose sodium as super disintegrant and Eudragit L 100 and Eudragit S 100 as a coating polymers. Formulation M7 can provide site specific delivery with sigmoidal drug release.Books on Demand GmbH, Überseering 33, 22297 Hamburg 96 pp. Englisch. Seller Inventory # 9783659408816
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Design and Development of Time Dependent Montelukast Sodium Tablet
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LAP LAMBERT Academic Publishing, 2013
ISBN 10: 3659408816
ISBN 13: 9783659408816
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